2II4
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Coenzyme A-bound form
Summary for 2II4
Entry DOI | 10.2210/pdb2ii4/pdb |
Related | 2IHW 2II3 2II5 |
Descriptor | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, CHLORIDE ION, COENZYME A, ... (4 entities in total) |
Functional Keywords | cubic core, homo trimer, coa-bound form, transferase |
Biological source | Bos taurus (cattle) |
Cellular location | Mitochondrion matrix : P11181 |
Total number of polymer chains | 8 |
Total formula weight | 236378.32 |
Authors | Kato, M.,Wynn, R.M.,Chuang, J.L.,Brautigam, C.A.,Custorio, M.,Chuang, D.T. (deposition date: 2006-09-27, release date: 2006-12-26, Last modification date: 2024-02-21) |
Primary citation | Kato, M.,Wynn, R.M.,Chuang, J.L.,Brautigam, C.A.,Custorio, M.,Chuang, D.T. A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex. Embo J., 25:5983-5994, 2006 Cited by PubMed: 17124494DOI: 10.1038/sj.emboj.7601444 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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