2II4
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Coenzyme A-bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | polymer | 262 | 28726.6 | 8 | UniProt (P11181) Pfam (PF00198) | Bos taurus (cattle) | Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, E2, Dihydrolipoamide branched chain transacylase, BCKAD E2 subunit |
| 2 | AA, I, K, M, N... (H, A, B, C, D...) | CHLORIDE ION | non-polymer | 35.5 | 12 | Chemie (CL) | |||
| 3 | BA, J, L, O, R... (H, A, B, C, D...) | COENZYME A | non-polymer | 767.5 | 8 | Chemie (COA) | |||
| 4 | CA, DA, EA, FA, GA... (A, B, C, D, E...) | water | water | 18.0 | 292 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 162 - 421 (UniProt: P11181)
| PDB | External Database | Details |
|---|---|---|
| Gly 160 | - | cloning artifact |
| His 161 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 229812.6 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 6565.7 | |
| All* | Total formula weight | 236378.3 |
