2VRL
Structure of human MAO B in complex with benzylhydrazine
Summary for 2VRL
Entry DOI | 10.2210/pdb2vrl/pdb |
Related | 1GOS 1H8R 1OJ9 1OJA 1OJB 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C73 2C75 2C76 2V5Z 2V60 2V61 2VRM |
Descriptor | AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, TOLUENE, ... (4 entities in total) |
Functional Keywords | oxidoreductase, fad, flavin, membrane, hydrazine, acetylation, flavoprotein, mitochondrion, transmembrane, inhibitor binding, membrane protein, monoamine oxidase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P27338 |
Total number of polymer chains | 2 |
Total formula weight | 119430.84 |
Authors | Binda, C.,Wang, J.,Li, M.,Hubalek, F.,Mattevi, A.,Edmondson, D.E. (deposition date: 2008-04-09, release date: 2008-04-22, Last modification date: 2011-07-13) |
Primary citation | Binda, C.,Wang, J.,Li, M.,Hubalek, F.,Mattevi, A.,Edmondson, D.E. Structural and Mechanistic Studies of Arylalkylhydrazine Inhibition of Human Monoamine Oxidases a and B Biochemistry, 47:5616-, 2008 Cited by PubMed: 18426226DOI: 10.1021/BI8002814 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report