3Q2M

Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, Protein Kinase Inhibitor CKI-7 Complex

Summary for 3Q2M

Entry DOI	10.2210/pdb3q2m/pdb
Related	3I0O 3I0Q 3I1A
Descriptor	Spectinomycin phosphotransferase, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE, NICKEL (II) ION, ... (4 entities in total)
Functional Keywords	ser/thr/tyr protein kinase, phosphotransferase, phosphorylation, cytosol, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Legionella pneumophila 130b
Total number of polymer chains	1
Total formula weight	39989.26
Authors	Berghuis, A.M.,Fong, D.H.,Xiong, B.,Hwang, J. (deposition date: 2010-12-20, release date: 2011-05-18, Last modification date: 2023-09-13)
Primary citation	Fong, D.H.,Xiong, B.,Hwang, J.,Berghuis, A.M. Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. Plos One, 6:e19589-e19589, 2011 Cited by PubMed: 21573013 DOI: 10.1371/journal.pone.0019589 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation