2ZKJ
Crystal structure of human PDK4-ADP complex
Summary for 2ZKJ
Entry DOI | 10.2210/pdb2zkj/pdb |
Related | 3D2R |
Descriptor | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | protein-nucleotide complex, homodimer, ghkl superfamily, carbohydrate metabolism, glucose metabolism, kinase, mitochondrion, phosphoprotein, transferase, transit peptide |
Biological source | Homo sapiens (Human) |
Cellular location | Mitochondrion matrix: Q16654 |
Total number of polymer chains | 2 |
Total formula weight | 90642.92 |
Authors | Kato, M.,Wynn, R.M.,Chuang, J.L.,Tso, S.-C.,Li, J.,Chuang, D.T. (deposition date: 2008-03-25, release date: 2008-08-05, Last modification date: 2023-11-01) |
Primary citation | Wynn, R.M.,Kato, M.,Chuang, J.L.,Tso, S.-C.,Li, J.,Chuang, D.T. Pyruvate Dehydrogenase Kinase-4 Structures Reveal a Metastable Open Conformation Fostering Robust Core-free Basal Activity J.Biol.Chem., 283:25305-25315, 2008 Cited by PubMed: 18658136DOI: 10.1074/jbc.M802249200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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