5ME0
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![BU of 5me0 by Molmil](/molmil-images/mine/5me0) | Structure of the 30S Pre-Initiation Complex 1 (30S IC-1) Stalled by GE81112 | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S. | 登録日 | 2016-11-14 | 公開日 | 2017-01-11 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (13.5 Å) | 主引用文献 | Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways. Nucleic Acids Res., 45, 2017
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6ZM5
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![BU of 6zm5 by Molmil](/molmil-images/mine/6zm5) | Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide | 分子名称: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | 著者 | Itoh, Y, Andrell, J, Amunts, A. | 登録日 | 2020-07-01 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Mechanism of membrane-tethered mitochondrial protein synthesis. Science, 371, 2021
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6Y3O
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![BU of 6y3o by Molmil](/molmil-images/mine/6y3o) | 14-3-3 Sigma in complex with phosphorylated CAMKK2 peptide | 分子名称: | 14-3-3 protein sigma, CALCIUM ION, CAMKK2, ... | 著者 | Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. | 登録日 | 2020-02-18 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
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7PPZ
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![BU of 7ppz by Molmil](/molmil-images/mine/7ppz) | Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form A | 分子名称: | Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I | 著者 | Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W. | 登録日 | 2021-09-15 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1. Commun Biol, 5, 2022
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6Y5W
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![BU of 6y5w by Molmil](/molmil-images/mine/6y5w) | Crystal structure of the envelope glycoprotein complex of Andes virus in a near postfusion conformation | 分子名称: | Envelope polyprotein,Envelope polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Serris, A, Rey, F.A, Guardado-Calvo, P. | 登録日 | 2020-02-26 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell, 183, 2020
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4UMU
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![BU of 4umu by Molmil](/molmil-images/mine/4umu) | Structure of MELK in complex with inhibitors | 分子名称: | (2-ethoxy-4-{[3-(isoquinolin-7-yl)prop-2-yn-1-yl]oxy}phenyl)methanaminium, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | 著者 | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | 登録日 | 2014-05-21 | 公開日 | 2014-10-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper Kinase. Acs Med.Chem.Lett., 6, 2015
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4V1A
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![BU of 4v1a by Molmil](/molmil-images/mine/4v1a) | Structure of the large subunit of the mammalian mitoribosome, part 2 of 2 | 分子名称: | MITORIBOSOMAL PROTEIN ML37, MRPL37, MITORIBOSOMAL PROTEIN ML38, ... | 著者 | Greber, B.J, Boehringer, D, Leibundgut, M, Bieri, P, Leitner, A, Schmitz, N, Aebersold, R, Ban, N. | 登録日 | 2014-09-25 | 公開日 | 2014-10-08 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome Nature, 515, 2014
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6WIE
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![BU of 6wie by Molmil](/molmil-images/mine/6wie) | Post-catalytic nicked complex of human Polymerase Mu on a complementary DNA double-strand break substrate | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*CP*G)-3'), ... | 著者 | Kaminski, A.M, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | 登録日 | 2020-04-09 | 公開日 | 2020-10-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural snapshots of human DNA polymerase mu engaged on a DNA double-strand break. Nat Commun, 11, 2020
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8FTO
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4UUV
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![BU of 4uuv by Molmil](/molmil-images/mine/4uuv) | Structure of the DNA binding ETS domain of human ETV4 in complex with DNA | 分子名称: | 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP)-3', ETS TRANSLOCATION VARIANT 4 | 著者 | Newman, J.A, Cooper, C.D.O, Kopec, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | 登録日 | 2014-07-31 | 公開日 | 2014-08-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation. J.Biol.Chem., 290, 2015
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4V11
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![BU of 4v11 by Molmil](/molmil-images/mine/4v11) | Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84 | 分子名称: | CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ... | 著者 | Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R. | 登録日 | 2014-09-22 | 公開日 | 2015-02-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1. J.Neurosci., 35, 2015
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4UUL
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6WT6
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![BU of 6wt6 by Molmil](/molmil-images/mine/6wt6) | Structure of a metazoan TIR-STING receptor from C. gigas | 分子名称: | Metazoan TIR-STING fusion | 著者 | Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J. | 登録日 | 2020-05-01 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | STING cyclic dinucleotide sensing originated in bacteria. Nature, 586, 2020
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6Y57
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![BU of 6y57 by Molmil](/molmil-images/mine/6y57) | Structure of human ribosome in hybrid-PRE state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-25 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
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4W1T
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6YG1
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![BU of 6yg1 by Molmil](/molmil-images/mine/6yg1) | Crystal structure of MKK7 (MAP2K7) in an active state, allosterically triggered by the N-terminal helix | 分子名称: | 1,2-ETHANEDIOL, Dual specificity mitogen-activated protein kinase kinase 7, SODIUM ION | 著者 | Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC), Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2020-03-27 | 公開日 | 2020-08-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities. Cell Chem Biol, 27, 2020
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5ME1
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![BU of 5me1 by Molmil](/molmil-images/mine/5me1) | Structure of the 30S Pre-Initiation Complex 2 (30S IC-2) Stalled by GE81112 | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S. | 登録日 | 2016-11-14 | 公開日 | 2017-01-11 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (13.5 Å) | 主引用文献 | Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways. Nucleic Acids Res., 45, 2017
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4W9N
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![BU of 4w9n by Molmil](/molmil-images/mine/4w9n) | Enoyl-acyl carrier protein-reductase domain from human fatty acid synthase complexed with triclosan | 分子名称: | CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase, IMIDAZOLE, ... | 著者 | Sippel, K.H, Vyas, N.K, Sankaran, B, Quiocho, F.A. | 登録日 | 2014-08-27 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Crystal structure of the human Fatty Acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition. J.Biol.Chem., 289, 2014
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5MLC
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![BU of 5mlc by Molmil](/molmil-images/mine/5mlc) | Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions | 分子名称: | 23S ribosomal RNA, chloroplastic, 4.8S ribosomal RNA, ... | 著者 | Graf, M, Arenz, S, Huter, P, Doenhoefer, A, Novacek, J, Wilson, D.N. | 登録日 | 2016-12-06 | 公開日 | 2016-12-28 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions. Nucleic Acids Res., 45, 2017
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6P5T
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![BU of 6p5t by Molmil](/molmil-images/mine/6p5t) | Surface-layer (S-layer) RsaA protein from Caulobacter crescentus bound to strontium and iodide | 分子名称: | IODIDE ION, S-layer protein, STRONTIUM ION | 著者 | Chan, A.C, Herrmann, J, Smit, J, Wakatsuki, S, Murphy, M.E. | 登録日 | 2019-05-30 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
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7PGD
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![BU of 7pgd by Molmil](/molmil-images/mine/7pgd) | PAF in 50 v/v % DMSO-water solution | 分子名称: | Pc24g00380 protein | 著者 | Czajlik, A, Batta, G. | 登録日 | 2021-08-13 | 公開日 | 2022-08-24 | 最終更新日 | 2023-02-15 | 実験手法 | SOLUTION NMR | 主引用文献 | DMSO-Induced Unfolding of the Antifungal Disulfide Protein PAF and Its Inactive Variant: A Combined NMR and DSC Study. Int J Mol Sci, 24, 2023
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5MRF
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![BU of 5mrf by Molmil](/molmil-images/mine/5mrf) | Structure of the yeast mitochondrial ribosome - Class C | 分子名称: | 15S ribosomal RNA, 21S ribosomal RNA, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Desai, N, Brown, A, Amunts, A, Ramakrishnan, V. | 登録日 | 2016-12-22 | 公開日 | 2017-02-15 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.97 Å) | 主引用文献 | The structure of the yeast mitochondrial ribosome. Science, 355, 2017
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6XKQ
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![BU of 6xkq by Molmil](/molmil-images/mine/6xkq) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-250 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CV07-250 Heavy Chain, CV07-250 Light Chain, ... | 著者 | Yuan, M, Liu, H, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-06-26 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model. Cell, 183, 2020
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6XLR
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6XU4
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![BU of 6xu4 by Molmil](/molmil-images/mine/6xu4) | Crystal structure of the genetically-encoded FGCaMP calcium indicator in its calcium-bound state | 分子名称: | CALCIUM ION, FGCamp | 著者 | Boyko, K.M, Nikolaeva, A.Y, Korzhenevskiy, D.A, Barykina, N.V, Subach, O.M, Subach, F.V. | 登録日 | 2020-01-17 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | FGCaMP7, an Improved Version of Fungi-Based Ratiometric Calcium Indicator for In Vivo Visualization of Neuronal Activity. Int J Mol Sci, 21, 2020
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