4UUV
Structure of the DNA binding ETS domain of human ETV4 in complex with DNA
Summary for 4UUV
Entry DOI | 10.2210/pdb4uuv/pdb |
Descriptor | ETS TRANSLOCATION VARIANT 4, 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP)-3', ... (4 entities in total) |
Functional Keywords | transcription |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: P43268 |
Total number of polymer chains | 24 |
Total formula weight | 142820.61 |
Authors | Newman, J.A.,Cooper, C.D.O.,Kopec, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Gileadi, O. (deposition date: 2014-07-31, release date: 2014-08-13, Last modification date: 2024-01-10) |
Primary citation | Cooper, C.D.O.,Newman, J.A.,Aitkenhead, H.,Allerston, C.K.,Gileadi, O. Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation. J.Biol.Chem., 290:13692-, 2015 Cited by PubMed: 25866208DOI: 10.1074/JBC.M115.646737 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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