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4UUV

Structure of the DNA binding ETS domain of human ETV4 in complex with DNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
A0006357biological_processregulation of transcription by RNA polymerase II
A0043565molecular_functionsequence-specific DNA binding
D0003700molecular_functionDNA-binding transcription factor activity
D0006355biological_processregulation of DNA-templated transcription
D0006357biological_processregulation of transcription by RNA polymerase II
D0043565molecular_functionsequence-specific DNA binding
G0003700molecular_functionDNA-binding transcription factor activity
G0006355biological_processregulation of DNA-templated transcription
G0006357biological_processregulation of transcription by RNA polymerase II
G0043565molecular_functionsequence-specific DNA binding
J0003700molecular_functionDNA-binding transcription factor activity
J0006355biological_processregulation of DNA-templated transcription
J0006357biological_processregulation of transcription by RNA polymerase II
J0043565molecular_functionsequence-specific DNA binding
M0003700molecular_functionDNA-binding transcription factor activity
M0006355biological_processregulation of DNA-templated transcription
M0006357biological_processregulation of transcription by RNA polymerase II
M0043565molecular_functionsequence-specific DNA binding
P0003700molecular_functionDNA-binding transcription factor activity
P0006355biological_processregulation of DNA-templated transcription
P0006357biological_processregulation of transcription by RNA polymerase II
P0043565molecular_functionsequence-specific DNA binding
S0003700molecular_functionDNA-binding transcription factor activity
S0006355biological_processregulation of DNA-templated transcription
S0006357biological_processregulation of transcription by RNA polymerase II
S0043565molecular_functionsequence-specific DNA binding
V0003700molecular_functionDNA-binding transcription factor activity
V0006355biological_processregulation of DNA-templated transcription
V0006357biological_processregulation of transcription by RNA polymerase II
V0043565molecular_functionsequence-specific DNA binding
Functional Information from PROSITE/UniProt
site_idPS00345
Number of Residues9
DetailsETS_DOMAIN_1 Ets-domain signature 1. LWQFLVALL
ChainResidueDetails
ALEU343-LEU351

site_idPS00346
Number of Residues16
DetailsETS_DOMAIN_2 Ets-domain signature 2. RpaMnYDkLSRSLRyY
ChainResidueDetails
AARG387-TYR402

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues640
DetailsDNA_BIND: ETS => ECO:0000255|PROSITE-ProRule:PRU00237
ChainResidueDetails
ALEU341-VAL421
DLEU341-VAL421
GLEU341-VAL421
JLEU341-VAL421
MLEU341-VAL421
PLEU341-VAL421
SLEU341-VAL421
VLEU341-VAL421

218853

PDB entries from 2024-04-24

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