6WIE

Post-catalytic nicked complex of human Polymerase Mu on a complementary DNA double-strand break substrate

Summary for 6WIE

Entry DOI	10.2210/pdb6wie/pdb
Descriptor	DNA-directed DNA/RNA polymerase mu, PYROPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... (14 entities in total)
Functional Keywords	family x polymerase, nonhomologous end-joining, dna double-strand break repair, transferase-dna complex, transferase/dna
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	46383.82
Authors	Kaminski, A.M.,Kunkel, T.A.,Pedersen, L.C.,Bebenek, K. (deposition date: 2020-04-09, release date: 2020-10-07, Last modification date: 2023-10-18)
Primary citation	Kaminski, A.M.,Pryor, J.M.,Ramsden, D.A.,Kunkel, T.A.,Pedersen, L.C.,Bebenek, K. Structural snapshots of human DNA polymerase mu engaged on a DNA double-strand break. Nat Commun, 11:4784-4784, 2020 Cited by PubMed: 32963245 DOI: 10.1038/s41467-020-18506-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation