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PDB: 1 results

6YG1
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BU of 6yg1 by Molmil
Crystal structure of MKK7 (MAP2K7) in an active state, allosterically triggered by the N-terminal helix
Descriptor: 1,2-ETHANEDIOL, Dual specificity mitogen-activated protein kinase kinase 7, SODIUM ION
Authors:Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC), Scottish Structural Proteomics Facility (SSPF)
Deposit date:2020-03-27
Release date:2020-08-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities.
Cell Chem Biol, 27, 2020

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