4V11
Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84
Summary for 4V11
Entry DOI | 10.2210/pdb4v11/pdb |
Descriptor | SYNAPTOTAGMIN-1, SYNAPTIC VESICLE GLYCOPROTEIN 2A, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | signaling protein |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein : P21579 Cell junction, synapse : Q7L0J3 |
Total number of polymer chains | 2 |
Total formula weight | 18463.23 |
Authors | Zhang, N.,Gordon, S.L.,Fritsch, M.J.,Esoof, N.,Campbell, D.,Gourlay, R.,Velupillai, S.,Macartney, T.,Peggie, M.,vanAalten, D.M.F.,Cousin, M.A.,Alessi, D.R. (deposition date: 2014-09-22, release date: 2015-02-25, Last modification date: 2024-01-10) |
Primary citation | Zhang, N.,Gordon, S.L.,Fritsch, M.J.,Esoof, N.,Campbell, D.G.,Gourlay, R.,Velupillai, S.,Macartney, T.,Peggie, M.,Van Aalten, D.M.F.,Cousin, M.A.,Alessi, D.R. Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1. J.Neurosci., 35:2492-, 2015 Cited by PubMed: 25673844DOI: 10.1523/JNEUROSCI.4248-14.2015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report