7N9F
| Structure of the in situ yeast NPC | 分子名称: | Dynein light chain 1, cytoplasmic, Nucleoporin 145c, ... | 著者 | Villa, E, Singh, D, Ludtke, S.J, Akey, C.W, Rout, M.P, Echeverria, I, Suslov, S. | 登録日 | 2021-06-17 | 公開日 | 2022-01-26 | 最終更新日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY (37 Å) | 主引用文献 | Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell, 185, 2022
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6WKX
| Cryo-EM of Form 1 related peptide filament, 15-10-3 | 分子名称: | peptide 15-10-3 | 著者 | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-17 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL0
| Cryo-EM of Form 1 related peptide filament, 36-31-3-RD | 分子名称: | peptide 36-31-3-RD | 著者 | Wang, F, Gnewou, O.M, Su, Z, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-17 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WL9
| Cryo-EM of Form 2 like peptide filament, Form2a | 分子名称: | peptide Form2a | 著者 | Wang, F, Beltran, L.C, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-18 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6WKY
| Cryo-EM of Form 1 related peptide filament, 29-24-3 | 分子名称: | peptide 29-24-3 | 著者 | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-17 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
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6FTR
| Serial Femtosecond Crystallography at Megahertz pulse rates | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Wiedorn, M.O, Oberthuer, D, Barty, A, Chapman, H.N. | 登録日 | 2018-02-23 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.76000106 Å) | 主引用文献 | Megahertz serial crystallography. Nat Commun, 9, 2018
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8EFP
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6UMI
| Crystal structure of erenumab Fab-b | 分子名称: | erenumab Fab heavy chain, IgG1, erenumab Fab light chain | 著者 | Mohr, C. | 登録日 | 2019-10-09 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab). Cell Rep, 30, 2020
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6UMH
| Crystal structure of erenumab Fab-a | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,3-PROPANDIOL, PHOSPHATE ION, ... | 著者 | Mohr, C. | 登録日 | 2019-10-09 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab). Cell Rep, 30, 2020
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6UMJ
| Crystal structure of erenumab Fab-c | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,3-BUTANEDIOL, erenumab Fab heavy chain, ... | 著者 | Mohr, C. | 登録日 | 2019-10-09 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab). Cell Rep, 30, 2020
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8ET1
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6UMG
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8ET2
| CryoEM structure of the GSDMB pore | 分子名称: | Isoform 1 of Gasdermin-B | 著者 | Wang, C, Ruan, J. | 登録日 | 2022-10-15 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (4.96 Å) | 主引用文献 | Structural basis for GSDMB pore formation and its targeting by IpaH7.8. Nature, 616, 2023
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6U57
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7TUM
| Multi-Hit SFX using MHz XFEL sources- first hit | 分子名称: | 1,2-ETHANEDIOL, Lysozyme C, SODIUM ION | 著者 | Darmanin, C, Holmes, S, Abbey, B. | 登録日 | 2022-02-03 | 公開日 | 2022-07-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.202 Å) | 主引用文献 | Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers. Nat Commun, 13, 2022
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6KJU
| Huge conformation shift of Vibrio cholerae VqmA dimer in the absence of target DNA provides insight into DNA-binding mechanisms of LuxR-type receptors | 分子名称: | 3,5-dimethylpyrazin-2-ol, Helix-turn-helix transcriptional regulator | 著者 | Wu, H, Li, M.J, Guo, H.J, Zhou, H, Wang, W.W, Xu, Q, Xu, C.Y, Yu, F, He, J.H. | 登録日 | 2019-07-23 | 公開日 | 2019-11-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Large conformation shifts of Vibrio cholerae VqmA dimer in the absence of target DNA provide insight into DNA-binding mechanisms of LuxR-type receptors. Biochem.Biophys.Res.Commun., 520, 2019
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8WZB
| RS head-neck monomer | 分子名称: | DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ... | 著者 | Meng, X, Cong, Y. | 登録日 | 2023-11-01 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia. Nat Commun, 15, 2024
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8X2U
| Radial spoke head-neck dimer | 分子名称: | DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ... | 著者 | Meng, X, Cong, Y. | 登録日 | 2023-11-10 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia. Nat Commun, 15, 2024
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3BC5
| X-ray crystal structure of human ppar gamma with 2-(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-2-phenyl-2h-1,2,3-triazol-4-yl)acetic acid | 分子名称: | (5-{3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]benzyl}-2-phenyl-2H-1,2,3-triazol-4-yl)acetic acid, Peroxisome proliferator-activated receptor gamma | 著者 | Muckelbauer, J.K. | 登録日 | 2007-11-12 | 公開日 | 2008-11-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Design, synthesis and structure-activity relationships of azole acids as novel, potent dual PPAR alpha/gamma agonists. Bioorg.Med.Chem.Lett., 19, 2009
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3T10
| HSP90 N-terminal domain bound to ACP | 分子名称: | Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Li, J. | 登録日 | 2011-07-21 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Structure insights into mechanisms of ATP hydrolysis and the activation of human heat-shock protein 90. Acta Biochim Biophys Sin (Shanghai), 44, 2012
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3T0H
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3T0Z
| Hsp90 N-terminal domain bound to ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-alpha, MAGNESIUM ION | 著者 | Li, J. | 登録日 | 2011-07-21 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.192 Å) | 主引用文献 | Structure insights into mechanisms of ATP hydrolysis and the activation of human heat-shock protein 90. Acta Biochim Biophys Sin (Shanghai), 44, 2012
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6OMT
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3PMT
| Crystal structure of the Tudor domain of human Tudor domain-containing protein 3 | 分子名称: | TETRAETHYLENE GLYCOL, Tudor domain-containing protein 3 | 著者 | Lam, R, Bian, C.B, Guo, Y.H, Xu, C, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-18 | 公開日 | 2010-12-01 | 最終更新日 | 2023-05-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30. Plos One, 7, 2012
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2O9Q
| The crystal structure of Bovine Trypsin complexed with a small inhibition peptide ORB2K | 分子名称: | CALCIUM ION, Cationic trypsin, ORB2K, ... | 著者 | Li, J, Zhang, C, Xu, X, Wang, J, Gong, W, Lai, R. | 登録日 | 2006-12-14 | 公開日 | 2007-12-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | From protease inhibitor to antibiotics: single point mutation makes tremendous functional shift To be Published
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