8ET2

CryoEM structure of the GSDMB pore

Summary for 8ET2

Entry DOI	10.2210/pdb8et2/pdb
EMDB information	28584
Descriptor	Isoform 1 of Gasdermin-B (1 entity in total)
Functional Keywords	pore-forming protein, gsdmb, pyroptosis, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	24
Total formula weight	1124358.00
Authors	Wang, C.,Ruan, J. (deposition date: 2022-10-15, release date: 2023-03-29, Last modification date: 2023-05-03)
Primary citation	Wang, C.,Shivcharan, S.,Tian, T.,Wright, S.,Ma, D.,Chang, J.,Li, K.,Song, K.,Xu, C.,Rathinam, V.A.,Ruan, J. Structural basis for GSDMB pore formation and its targeting by IpaH7.8. Nature, 616:590-597, 2023 Cited by PubMed: 36991122 DOI: 10.1038/s41586-023-05832-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.96 Å)

Structure validation