6KJU

Huge conformation shift of Vibrio cholerae VqmA dimer in the absence of target DNA provides insight into DNA-binding mechanisms of LuxR-type receptors

Summary for 6KJU

• Entry DOI: 10.2210/pdb6kju/pdb
• Descriptor: Helix-turn-helix transcriptional regulator, 3,5-dimethylpyrazin-2-ol (3 entities in total)
• Functional Keywords: vibrio cholera, quorum sensing, transcription regulator, transcription
• Biological source: Vibrio cholerae
• Total number of polymer chains: 2
• Total formula weight: 57499.88

Authors

Wu, H.,Li, M.J.,Guo, H.J.,Zhou, H.,Wang, W.W.,Xu, Q.,Xu, C.Y.,Yu, F.,He, J.H. (deposition date: 2019-07-23, release date: 2019-11-13, Last modification date: 2023-11-22)

• Primary citation: Wu, H.,Li, M.,Peng, C.,Yin, Y.,Guo, H.,Wang, W.,Xu, Q.,Zhou, H.,Xu, C.,Yu, F.,He, J.; Large conformation shifts of Vibrio cholerae VqmA dimer in the absence of target DNA provide insight into DNA-binding mechanisms of LuxR-type receptors.; Biochem.Biophys.Res.Commun., 520:399-405, 2019; PubMed: 31606206; DOI: 10.1016/j.bbrc.2019.10.063

Experimental method

X-RAY DIFFRACTION (1.75 Å)