4YQ2
| |
4YQ9
| |
4YQK
| Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds | 分子名称: | 4-amino-N-(piperidin-4-yl)-1,2,5-oxadiazole-3-carboxamide, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Elkins, P.A, Bonnette, W.G, Madauss, K.P, Stuckey, J.A. | 登録日 | 2015-03-13 | 公開日 | 2016-03-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds To Be Published
|
|
4YQT
| |
5COY
| Crystal structure of CC chemokine 5 (CCL5) | 分子名称: | C-C motif chemokine 5, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | 著者 | Liang, W.G, Tang, W. | 登録日 | 2015-07-20 | 公開日 | 2016-04-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.443 Å) | 主引用文献 | Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5CMD
| |
5CJO
| |
5D9F
| |
5D65
| X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) WITH HEPARIN COMPLEX | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-C motif chemokine 3, CHLORIDE ION, ... | 著者 | Liang, W.G, Hwang, D.Y, Zulueta, M.M, Hung, S.C, Tang, W. | 登録日 | 2015-08-11 | 公開日 | 2016-04-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5DNF
| Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, C-C motif chemokine 5, ... | 著者 | Liang, W.G, Tang, W. | 登録日 | 2015-09-10 | 公開日 | 2016-04-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.549 Å) | 主引用文献 | Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
1RQC
| Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design | 分子名称: | COBALT (II) ION, formylmethionine deformylase | 著者 | Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G. | 登録日 | 2003-12-04 | 公開日 | 2004-01-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An improved crystal form of Plasmodium falciparum peptide deformylase Protein Sci., 13, 2004
|
|
1TV6
| HIV-1 Reverse Transcriptase Complexed with CP-94,707 | 分子名称: | 3-[4-(2-METHYL-IMIDAZO[4,5-C]PYRIDIN-1-YL)BENZYL]-3H-BENZOTHIAZOL-2-ONE, reverse transcriptase p51 subunit, reverse transcriptase p66 subunit | 著者 | Pata, J.D, Stirtan, W.G, Goldstein, S.W, Steitz, T.A. | 登録日 | 2004-06-28 | 公開日 | 2004-07-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant RTs resistant to other non-nucleoside inhibitors Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1VCB
| |
4HSV
| Crystal Structure of CXCL4L1 | 分子名称: | Platelet factor 4 variant | 著者 | Kuo, J.H, Liu, J.S, Wu, W.G, Sue, S.C. | 登録日 | 2012-10-30 | 公開日 | 2013-04-10 | 最終更新日 | 2013-07-31 | 実験手法 | X-RAY DIFFRACTION (2.083 Å) | 主引用文献 | Alternative C-terminal helix orientation alters chemokine function: structure of the anti-angiogenic chemokine, CXCL4L1 J.Biol.Chem., 288, 2013
|
|
2PMW
| The Crystal Structure of Proprotein convertase subtilisin kexin type 9 (PCSK9) | 分子名称: | Proprotein convertase subtilisin/kexin type 9, SULFATE ION | 著者 | Piper, D.E, Romanow, W.G, Thibault, S.T, Walker, N.P.C. | 登録日 | 2007-04-23 | 公開日 | 2007-05-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol. Structure, 15, 2007
|
|
4IFH
| Crystal structure of human insulin degrading enzyme (IDE) in complex with compound BDM44619 | 分子名称: | Insulin-degrading enzyme, N-({1-[(2R)-4-(hydroxyamino)-1-(naphthalen-2-yl)-4-oxobutan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)-4-methylbenzamide, ZINC ION | 著者 | Liang, W.G, Guo, Q, Deprez, R, Deprez, B, Tang, W. | 登録日 | 2012-12-14 | 公開日 | 2013-12-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.286 Å) | 主引用文献 | Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Nat Commun, 6, 2015
|
|
4IOF
| Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE) | 分子名称: | Fab-bound IDE, heavy chain, light chain, ... | 著者 | McCord, L.A, Liang, W.G, Hoey, R, Dowdell, E, Koide, A, Koide, S, Tang, W.J. | 登録日 | 2013-01-07 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.353 Å) | 主引用文献 | Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
2QUS
| |
2QUW
| |
4K7A
| |
4KSR
| Crystal Structure of the Vibrio cholerae ATPase GspE Hexamer | 分子名称: | Type II secretion system protein E, Hemolysin-coregulated protein | 著者 | Hol, W.G, Turley, S, Lu, C.Y, Park, Y.J, Marionni, S.T, Lee, K, Patrick, M, Sandkvist, M, Bush, M, Shah, R. | 登録日 | 2013-05-17 | 公開日 | 2013-09-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Hexamers of the Type II Secretion ATPase GspE from Vibrio cholerae with Increased ATPase Activity. Structure, 21, 2013
|
|
4KGO
| |
4KSS
| Crystal Structure of Vibrio cholerae ATPase GspsE Hexamer | 分子名称: | Type II secretion system protein E, hemolysin-coregulated protein | 著者 | Hol, W.G, Turley, S, Lu, C.Y, Park, Y.J. | 登録日 | 2013-05-17 | 公開日 | 2013-09-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (7.58 Å) | 主引用文献 | Hexamers of the Type II Secretion ATPase GspE from Vibrio cholerae with Increased ATPase Activity. Structure, 21, 2013
|
|
4KGH
| |
4K59
| |