4KGO

Crystal Structure of double Leucine to Methionine mutant human splunc1 lacking the secretion signal sequence

Summary for 4KGO

• Entry DOI: 10.2210/pdb4kgo/pdb
• Related: 4KGH
• Descriptor: BPI fold-containing family A member 1 (1 entity in total)
• Functional Keywords: beta barrel; bpi-like fold, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted : Q9NP55
• Total number of polymer chains: 2
• Total formula weight: 50244.12

Authors

Betts, L.,Walton, W.G. (deposition date: 2013-04-29, release date: 2013-09-25, Last modification date: 2017-11-15)

• Primary citation: Garland, A.L.,Walton, W.G.,Coakley, R.D.,Tan, C.D.,Gilmore, R.C.,Hobbs, C.A.,Tripathy, A.,Clunes, L.A.,Bencharit, S.,Stutts, M.J.,Betts, L.,Redinbo, M.R.,Tarran, R.; Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.; Proc.Natl.Acad.Sci.USA, 110:15973-15978, 2013; PubMed: 24043776; DOI: 10.1073/pnas.1311999110

Experimental method

X-RAY DIFFRACTION (3.194 Å)