5D65

X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) WITH HEPARIN COMPLEX

Summary for 5D65

• Entry DOI: 10.2210/pdb5d65/pdb
• Related: 5CMD 5COR 5COY 5DNF
• Descriptor: C-C motif chemokine 3, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: cc chemokine, ccl3, oligomer, signaling protein, heparin, gag, complex, cytokine
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 5
• Total formula weight: 42031.76

Authors

Liang, W.G.,Hwang, D.Y.,Zulueta, M.M.,Hung, S.C.,Tang, W. (deposition date: 2015-08-11, release date: 2016-04-20, Last modification date: 2023-09-27)

• Primary citation: Liang, W.G.,Triandafillou, C.G.,Huang, T.Y.,Zulueta, M.M.,Banerjee, S.,Dinner, A.R.,Hung, S.C.,Tang, W.J.; Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.; Proc.Natl.Acad.Sci.USA, 113:5000-5005, 2016; PubMed: 27091995; DOI: 10.1073/pnas.1523981113

Experimental method

X-RAY DIFFRACTION (3.1 Å)