5DNF

Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin

Summary for 5DNF

• Entry DOI: 10.2210/pdb5dnf/pdb
• Related: 5CMD 5COY
• Descriptor: C-C motif chemokine 5, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, alpha-D-galactopyranose, ... (8 entities in total)
• Functional Keywords: cc chemokine, high oligomer, cytokine
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 9
• Total formula weight: 73675.35

Authors

Liang, W.G.,Tang, W. (deposition date: 2015-09-10, release date: 2016-04-13, Last modification date: 2020-07-29)

• Primary citation: Liang, W.G.,Triandafillou, C.G.,Huang, T.Y.,Zulueta, M.M.,Banerjee, S.,Dinner, A.R.,Hung, S.C.,Tang, W.J.; Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.; Proc.Natl.Acad.Sci.USA, 113:5000-5005, 2016; PubMed: 27091995; DOI: 10.1073/pnas.1523981113

Experimental method

X-RAY DIFFRACTION (2.549 Å)