4HSV

Crystal Structure of CXCL4L1

Summary for 4HSV

• Entry DOI: 10.2210/pdb4hsv/pdb
• Related: 1F9Q
• Descriptor: Platelet factor 4 variant (2 entities in total)
• Functional Keywords: anti-angiogenesis, heparin, extracellular, antitumor protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P10720
• Total number of polymer chains: 4
• Total formula weight: 31817.43

Authors

Kuo, J.H.,Liu, J.S.,Wu, W.G.,Sue, S.C. (deposition date: 2012-10-30, release date: 2013-04-10, Last modification date: 2013-07-31)

• Primary citation: Kuo, J.H.,Chen, Y.P.,Liu, J.S.,Dubrac, A.,Quemener, C.,Prats, H.,Bikfalvi, A.,Wu, W.G.,Sue, S.C.; Alternative C-terminal helix orientation alters chemokine function: structure of the anti-angiogenic chemokine, CXCL4L1; J.Biol.Chem., 288:13522-13533, 2013; PubMed: 23536183; DOI: 10.1074/jbc.M113.455329

Experimental method

X-RAY DIFFRACTION (2.083 Å)