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5KLI
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Rhodobacter sphaeroides bc1 with stigmatellin and antimycin
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, (2R,3S,6S,7R,8R)-3-{[3-(FORMYLAMINO)-2-HYDROXYBENZOYL]AMINO}-8-HEXYL-2,6-DIMETHYL-4,9-DIOXO-1,5-DIOXONAN-7-YL (2S)-2-METHYLBUTANOATE, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-24
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.996 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
5KLV
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BU of 5klv by Molmil
Structure of bos taurus cytochrome bc1 with fenamidone inhibited
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ...
著者Xia, D, Esser, L, Zhou, F, Zhou, Y, Xiao, Y, Tang, W.K, Yu, C.A, Qin, Z.
登録日2016-06-25
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.652 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
5KKZ
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BU of 5kkz by Molmil
Rhodobacter sphaeroides bc1 with famoxadone
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, ASCORBIC ACID, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-23
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
8DFH
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BU of 8dfh by Molmil
Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
分子名称: 42C3 Fab Heavy Chain, 42C3 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFI
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BU of 8dfi by Molmil
Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
分子名称: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFG
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BU of 8dfg by Molmil
Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
分子名称: 42D6 Fab Heavy Chain, 42D6 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8E1Z
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BU of 8e1z by Molmil
Crystal structure of Plasmodium falciparum ookinete surface antigen Pfs28
分子名称: CHLORIDE ION, Ookinete surface protein Pfs28, SULFATE ION
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-08-12
公開日2022-11-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design.
Sci Rep, 12, 2022
8EZL
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BU of 8ezl by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-50
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ...
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZM
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BU of 8ezm by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-63
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ...
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZK
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BU of 8ezk by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-04
分子名称: 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-4, single-chain Fv
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
7JUM
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BU of 7jum by Molmil
Pfs230 D1 domain in complex with neutralizing antibody LMIV230-01
分子名称: Gametocyte surface protein P230, Neutralizing antibody, LMIV230-01 Single-chain Fv
著者Tolia, N, Tang, W.K.
登録日2020-08-20
公開日2021-03-31
最終更新日2021-04-07
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
Nat Commun, 12, 2021
4F33
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BU of 4f33 by Molmil
Crystal Structure of therapeutic antibody MORAb-009
分子名称: MORAb-009 FAB heavy chain, MORAb-009 FAB light chain, TETRAETHYLENE GLYCOL
著者Xia, D, Ma, J, Tang, W.K, Esser, L.
登録日2012-05-08
公開日2012-07-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
4F3F
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BU of 4f3f by Molmil
Crystal Structure of Msln7-64 MORAb-009 FAB complex
分子名称: MORAb-009 Fab heavy chain, MORAb-009 Fab light chain, Mesothelin
著者Xia, D, Pastan, I, Ma, J, Tang, W.K, Esser, L.
登録日2012-05-09
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
7U9J
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BU of 7u9j by Molmil
Crystal structure of Mesothelin-207 fragment
分子名称: GLYCEROL, Isoform 3 of Mesothelin, SULFATE ION
著者Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D.
登録日2022-03-10
公開日2023-02-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
7UED
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BU of 7ued by Molmil
Crystal structure of full length mesothelin bound with MORAb-009 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Isoform 4 of Mesothelin, ...
著者Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D.
登録日2022-03-21
公開日2023-02-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
3HU3
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BU of 3hu3 by Molmil
Structure of p97 N-D1 R155H mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Tang, W.-K.
登録日2009-06-12
公開日2010-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.
Embo J., 29, 2010
3HU2
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BU of 3hu2 by Molmil
Structure of p97 N-D1 R86A mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Tang, W.-K.
登録日2009-06-12
公開日2010-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.
Embo J., 29, 2010
3HU1
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BU of 3hu1 by Molmil
Structure of p97 N-D1 R95G mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Tang, W.-K.
登録日2009-06-12
公開日2010-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.
Embo J., 29, 2010
6UKO
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BU of 6uko by Molmil
Structure analysis of full-length mouse bcs1 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
著者Xia, D, Esser, L.
登録日2019-10-05
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
8CX3
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BU of 8cx3 by Molmil
Crystal structure of full-length mesothelin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Zhan, J, Esser, L, Xia, D.
登録日2022-05-19
公開日2023-02-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.609 Å)
主引用文献Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
8DCC
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BU of 8dcc by Molmil
SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 3 Bound to P2B-2F6 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2B-2F6 Fab heavy chain, P2B-2F6 Fab light chain, ...
著者Dickey, T.D, Tolia, N.H.
登録日2022-06-16
公開日2022-07-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response.
Sci Adv, 8, 2022
5KO2
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BU of 5ko2 by Molmil
Mouse pgp 34 linker deleted mutant Hg derivative
分子名称: MERCURY (II) ION, Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-06-29
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KOY
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BU of 5koy by Molmil
Mouse pgp 34 linker deleted bound with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-01
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KPD
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BU of 5kpd by Molmil
Mouse pgp 34 linker deleted double EQ mutant
分子名称: Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-03
公開日2016-11-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KPI
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BU of 5kpi by Molmil
Mouse native PGP
分子名称: Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-04
公開日2016-11-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.01 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017

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