7UED

Crystal structure of full length mesothelin bound with MORAb-009 Fab

Summary for 7UED

Entry DOI	10.2210/pdb7ued/pdb
Descriptor	Isoform 4 of Mesothelin, MORAb-009 Fab light chain, MORAb-009 Fab heavy chain, ... (7 entities in total)
Functional Keywords	mesothelin, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	82357.35
Authors	Zhan, J.,Esser, L.,Lin, D.,Tang, W.K.,Xia, D. (deposition date: 2022-03-21, release date: 2023-02-01, Last modification date: 2023-10-25)
Primary citation	Zhan, J.,Lin, D.,Watson, N.,Esser, L.,Tang, W.K.,Zhang, A.,Liu, X.,Hassan, R.,Gleinich, A.,Shajahan, A.,Azadi, P.,Pastan, I.,Xia, D. Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies. Cancer Res Commun, 3:175-191, 2023 Cited by PubMed: 36968141 DOI: 10.1158/2767-9764.CRC-22-0306 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation