4F33

Crystal Structure of therapeutic antibody MORAb-009

Summary for 4F33

• Entry DOI: 10.2210/pdb4f33/pdb
• Related: 4F3F
• Descriptor: MORAb-009 FAB light chain, MORAb-009 FAB heavy chain, TETRAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: igg, antigen binding, mesothelin, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 8
• Total formula weight: 192606.24

Authors

Xia, D.,Ma, J.,Tang, W.K.,Esser, L. (deposition date: 2012-05-08, release date: 2012-07-11, Last modification date: 2024-04-03)

• Primary citation: Ma, J.,Tang, W.K.,Esser, L.,Pastan, I.,Xia, D.; Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.; J.Biol.Chem., 287:33123-33131, 2012; PubMed: 22787150; DOI: 10.1074/jbc.M112.381756

Experimental method

X-RAY DIFFRACTION (1.749 Å)