4F3F

Crystal Structure of Msln7-64 MORAb-009 FAB complex

Summary for 4F3F

• Entry DOI: 10.2210/pdb4f3f/pdb
• Related: 4F33
• Descriptor: MORAb-009 Fab light chain, MORAb-009 Fab heavy chain, Mesothelin, ... (4 entities in total)
• Functional Keywords: antibody fab, recognize mesothelin, mesothelin, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 3
• Total formula weight: 55719.21

Authors

Xia, D.,Pastan, I.,Ma, J.,Tang, W.K.,Esser, L. (deposition date: 2012-05-09, release date: 2012-07-11, Last modification date: 2023-09-13)

• Primary citation: Ma, J.,Tang, W.K.,Esser, L.,Pastan, I.,Xia, D.; Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.; J.Biol.Chem., 287:33123-33131, 2012; PubMed: 22787150; DOI: 10.1074/jbc.M112.381756

Experimental method

X-RAY DIFFRACTION (2.65 Å)