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5YX9
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BU of 5yx9 by Molmil
Cryo-EM structure of human TRPC6 at 3.8A resolution
Descriptor: Short transient receptor potential channel 6
Authors:Chen, L, Tang, Q, Guo, W.
Deposit date:2017-12-02
Release date:2018-05-23
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the receptor-activated human TRPC6 and TRPC3 ion channels.
Cell Res., 28, 2018
7F1R
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BU of 7f1r by Molmil
Cryo-EM structure of the chemokine receptor CCR5 in complex with RANTES and Gi
Descriptor: C-C motif chemokine 5,C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B.
Deposit date:2021-06-09
Release date:2021-07-14
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5.
Nat Commun, 12, 2021
7F1T
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BU of 7f1t by Molmil
Crystal structure of the human chemokine receptor CCR5 in complex with MIP-1a
Descriptor: C-C motif chemokine 3,C-C chemokine receptor type 5,Rubredoxin,C-C chemokine receptor type 5, ZINC ION
Authors:Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B.
Deposit date:2021-06-09
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5.
Nat Commun, 12, 2021
7F1S
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BU of 7f1s by Molmil
Cryo-EM structure of the apo chemokine receptor CCR5 in complex with Gi
Descriptor: C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B.
Deposit date:2021-06-09
Release date:2021-07-14
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5.
Nat Commun, 12, 2021
7F1Q
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BU of 7f1q by Molmil
Cryo-EM structure of the chemokine receptor CCR5 in complex with MIP-1a and Gi
Descriptor: C-C motif chemokine 3,C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B.
Deposit date:2021-06-09
Release date:2021-07-14
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5.
Nat Commun, 12, 2021
3OKG
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BU of 3okg by Molmil
Crystal structure of HsdS subunit from Thermoanaerobacter tengcongensis
Descriptor: Restriction endonuclease S subunits, SULFATE ION
Authors:Liang, D, Gao, P, Tang, Q, An, X, Yan, X.
Deposit date:2010-08-24
Release date:2011-05-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of HsdS subunit from Thermoanaerobacter tengcongensis sheds lights on mechanism of dynamic opening and closing of type I methyltransferase
Plos One, 6, 2011
6IE2
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BU of 6ie2 by Molmil
Crystal structure of methyladenine demethylase
Descriptor: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, Nucleic acid dioxygenase ALKBH1
Authors:Tian, L.F, Tang, Q, Chen, Z.Z, Yan, X.X.
Deposit date:2018-09-13
Release date:2019-09-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of nucleic acid recognition and 6mA demethylation by human ALKBH1.
Cell Res., 30, 2020
6JDE
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BU of 6jde by Molmil
crystal structure of a DNA repair protein
Descriptor: Putative DNA repair helicase RadD, ZINC ION
Authors:Yan, X.X, Tang, Q.
Deposit date:2019-02-01
Release date:2019-06-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a novel ATPase RadD from Escherichia coli.
Proteins, 87, 2019
6IE3
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BU of 6ie3 by Molmil
Crystal structure of methyladenine demethylase
Descriptor: ETHANOL, MANGANESE (II) ION, Nucleic acid dioxygenase ALKBH1
Authors:Tian, L.F, Tang, Q, Chen, Z.Z, Yan, X.X.
Deposit date:2018-09-13
Release date:2019-09-18
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis of nucleic acid recognition and 6mA demethylation by human ALKBH1.
Cell Res., 30, 2020
2HZ5
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BU of 2hz5 by Molmil
Crystal structure of human dynein light chain Dnlc2A
Descriptor: CESIUM ION, Dynein light chain 2A, cytoplasmic
Authors:Liu, J.-F, Wang, Z.-X, Wang, X.-Q, Tang, Q, An, X.-M, Gui, L.-L, Liang, D.-C.
Deposit date:2006-08-08
Release date:2007-08-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human dynein light chain Dnlc2A: Structural insights into the interaction with IC74
Biochem.Biophys.Res.Commun., 349, 2006
3QAH
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BU of 3qah by Molmil
Crystal structure of apo-form human MOF catalytic domain
Descriptor: Probable histone acetyltransferase MYST1, ZINC ION
Authors:Sun, B, Tang, Q, Zhong, C, Ding, J.
Deposit date:2011-01-11
Release date:2011-07-06
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274
Cell Res., 21, 2011
5YBB
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BU of 5ybb by Molmil
Structural basis underlying complex assembly andconformational transition of the type I R-M system
Descriptor: DNA, Restriction endonuclease S subunits, S-ADENOSYLMETHIONINE, ...
Authors:Liu, Y.P, Tang, Q, Zhang, J.Z, Tian, L.F, Gao, P, Yan, X.X.
Deposit date:2017-09-04
Release date:2017-11-29
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis underlying complex assembly and conformational transition of the type I R-M system.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1YIM
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BU of 1yim by Molmil
Human estrogen receptor alpha ligand-binding domain in complex with compound 4
Descriptor: (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL, Estrogen receptor
Authors:Fitzgerald, P.M, Sharma, N.
Deposit date:2005-01-12
Release date:2005-07-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs.
Bioorg.Med.Chem.Lett., 15, 2005
1YIN
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BU of 1yin by Molmil
Human estrogen receptor alpha ligand-binding domain in complex with compound 3F
Descriptor: (2R,3R,4S)-5-FLUORO-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL, Estrogen receptor
Authors:Fitzgerald, P.M, Sharma, N.
Deposit date:2005-01-12
Release date:2005-07-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs.
Bioorg.Med.Chem.Lett., 15, 2005
4HWV
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BU of 4hwv by Molmil
Structure of Pectate Lyase from Acidovorax avenae subsp citrulli
Descriptor: CALCIUM ION, Pectate lyase/Amb allergen
Authors:Qun, T, Liqun, Z.
Deposit date:2012-11-09
Release date:2013-10-23
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:1.37 angstrom crystal structure of pathogenic factor pectate lyase from Acidovorax citrulli.
Proteins, 81, 2013
5CH8
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BU of 5ch8 by Molmil
Crystal structure of MDLA N225Q mutant form Penicillium cyclopium
Descriptor: CHLORIDE ION, GLYCEROL, Mono- and diacylglycerol lipase, ...
Authors:Xu, J, Xu, H, Hou, S, Liu, J.
Deposit date:2015-07-10
Release date:2016-04-20
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Lipase-Driven Epoxidation Is A Two-Stage Synergistic Process
ChemistrySelect, 4, 2016
6WHC
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BU of 6whc by Molmil
CryoEM Structure of the glucagon receptor with a dual-agonist peptide
Descriptor: Dual-agonist peptide, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Belousoff, M.J, Sexton, P, Danev, R.
Deposit date:2020-04-07
Release date:2020-05-27
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide.
J.Biol.Chem., 295, 2020
8WRZ
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BU of 8wrz by Molmil
Cry-EM structure of cannabinoid receptor-arrestin 2 complex
Descriptor: (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, Beta-arrestin-1, Soluble cytochrome b562,Cannabinoid receptor 1, ...
Authors:Wang, Y.X, Wang, T, Wu, L.J, Hua, T, Liu, Z.J.
Deposit date:2023-10-16
Release date:2024-02-28
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of cannabinoid receptor CB1-beta-arrestin complex.
Protein Cell, 15, 2024
7LSW
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BU of 7lsw by Molmil
Structure of Full Beta-Hairpin LIR from FNIP2 Bound to GABARAP
Descriptor: Folliculin-interacting protein 2,Gamma-aminobutyric acid receptor-associated protein, SULFATE ION
Authors:Appleton, B.A.
Deposit date:2021-02-18
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.
Sci Adv, 7, 2021
7LT6
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BU of 7lt6 by Molmil
Structure of Partial Beta-Hairpin LIR from FNIP2 Bound to GABARAP
Descriptor: Folliculin-interacting protein 2,Gamma-aminobutyric acid receptor-associated protein
Authors:Appleton, B.A.
Deposit date:2021-02-18
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.
Sci Adv, 7, 2021
7M33
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BU of 7m33 by Molmil
The structure of Bacillus subtilis BmrCD in the inward-facing conformation bound to Hoechst-33342 and ATP
Descriptor: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Thaker, T.M, Tomasiak, T.M.
Deposit date:2021-03-18
Release date:2022-01-05
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter.
Nat.Chem.Biol., 18, 2022
7X9B
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BU of 7x9b by Molmil
Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
7X9C
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BU of 7x9c by Molmil
Cryo-EM structure of neuropeptide Y Y4 receptor in complex with PP and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
7X9A
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BU of 7x9a by Molmil
Cryo-EM structure of neuropeptide Y Y1 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
7END
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BU of 7end by Molmil
Crystal structure of SARS-CoV 3CLpro in complex with the non-covalent inhibitor WU-04
Descriptor: Replicase polyprotein 1a, ~{N}-[(1~{S},2~{R})-2-[[4-bromanyl-2-(methylcarbamoyl)-6-nitro-phenyl]amino]cyclohexyl]isoquinoline-4-carboxamide
Authors:Hou, N, Peng, C, Hu, Q.
Deposit date:2021-04-16
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro.
Acs Cent.Sci., 9, 2023

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