6IE2

Crystal structure of methyladenine demethylase

Summary for 6IE2

Entry DOI	10.2210/pdb6ie2/pdb
Descriptor	Nucleic acid dioxygenase ALKBH1, MANGANESE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total)
Functional Keywords	demethylase, dna binding protein, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	8
Total formula weight	352709.76
Authors	Tian, L.F.,Tang, Q.,Chen, Z.Z.,Yan, X.X. (deposition date: 2018-09-13, release date: 2019-09-18, Last modification date: 2023-11-22)
Primary citation	Tian, L.F.,Liu, Y.P.,Chen, L.,Tang, Q.,Wu, W.,Sun, W.,Chen, Z.,Yan, X.X. Structural basis of nucleic acid recognition and 6mA demethylation by human ALKBH1. Cell Res., 30:272-275, 2020 Cited by PubMed: 32051559 DOI: 10.1038/s41422-019-0233-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation