7X9B

Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi

Summary for 7X9B

• Entry DOI: 10.2210/pdb7x9b/pdb
• EMDB information: 33070
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
• Functional Keywords: signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 135035.18

Authors

Tang, T.,Han, S.,Zhao, Q.,Wu, B. (deposition date: 2022-03-15, release date: 2022-05-18)

• Primary citation: Tang, T.,Tan, Q.,Han, S.,Diemar, A.,Lobner, K.,Wang, H.,Schuss, C.,Behr, V.,Morl, K.,Wang, M.,Chu, X.,Yi, C.,Keller, M.,Kofoed, J.,Reedtz-Runge, S.,Kaiser, A.,Beck-Sickinger, A.G.,Zhao, Q.,Wu, B.; Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.; Sci Adv, 8:eabm1232-eabm1232, 2022; PubMed: 35507650; DOI: 10.1126/sciadv.abm1232

Experimental method

ELECTRON MICROSCOPY (3.4 Å)