6JDE

crystal structure of a DNA repair protein

Summary for 6JDE

• Entry DOI: 10.2210/pdb6jde/pdb
• Descriptor: Putative DNA repair helicase RadD, ZINC ION (3 entities in total)
• Functional Keywords: dna repair protein, hydrolase
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 2
• Total formula weight: 133148.90

Authors

Yan, X.X.,Tang, Q. (deposition date: 2019-02-01, release date: 2019-06-26, Last modification date: 2024-03-27)

Primary citation

Kuang, X.,Tang, Q.,Liu, Y.P.,Yan, X.X.,Xu, W.
Crystal structure of a novel ATPase RadD from Escherichia coli.
Proteins, 87:791-795, 2019

PubMed Abstract: The helicase superfamily 2 (SF2) proteins are involved in essentially every step in DNA and RNA metabolism. The radD (yejH) gene, which belongs to SF2, plays an important role in DNA repair. The RadD protein includes all seven conserved SF2 motifs and has shown ATPase activity. Here, we first reported the structure of RadD from Escherichia coli containing two RecA-like domains, a zinc finger motif, and a C-terminal domain. Based on the structure of RadD and other SF2 proteins, we then built a model of the RedD-ATP complex.

PubMed: 31035307
DOI: 10.1002/prot.25704

Experimental method

X-RAY DIFFRACTION (2.8 Å)