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PDB: 13 results

3CIR
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BU of 3cir by Molmil
E. coli Quinol fumarate reductase FrdA T234A mutation
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tomasiak, T.M, Maklashina, E, Cecchini, G, Iverson, T.M.
Deposit date:2008-03-11
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:A threonine on the active site loop controls transition state formation in Escherichia coli respiratory complex II.
J.Biol.Chem., 283, 2008
3P4P
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BU of 3p4p by Molmil
Crystal structure of Menaquinol:fumarate oxidoreductase in complex with fumarate
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tomasiak, T.M, Archuleta, T.L, Andr ll, J, Luna-Ch vez, C, Davis, T.A, Sarwar, M, Ham, A.J, McDonald, W.H, Yankowskaya, V, Stern, H.A, Johnston, J.N, Maklashina, E, Cecchini, G, Iverson, T.M.
Deposit date:2010-10-06
Release date:2010-12-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
3P4Q
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BU of 3p4q by Molmil
Crystal structure of Menaquinol:oxidoreductase in complex with oxaloacetate
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tomasiak, T.M, Archuleta, T.L, Andrell, J, Luna-Chavez, C, Davis, T.A, Sarwar, M, Ham, A.J, McDonald, W.H, Yankowskaya, V, Stern, H.A, Johnston, J.N, Maklashina, E, Cecchini, G, Iverson, T.M.
Deposit date:2010-10-06
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
3P4R
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BU of 3p4r by Molmil
Crystal structure of Menaquinol:fumarate oxidoreductase in complex with glutarate
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tomasiak, T.M, Archuleta, T.L, Andrell, J, Luna-Chavez, C, Davis, T.A, Sarwar, M, Ham, A.J, McDonald, W.H, Yankowskaya, V, Stern, H.A, Johnston, J.N, Maklashina, E, Cecchini, G, Iverson, T.M.
Deposit date:2010-10-07
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
3P4S
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BU of 3p4s by Molmil
Crystal structure of Menaquinol:fumarate oxidoreductase in complex with a 3-nitropropionate adduct
Descriptor: 3-NITROPROPANOIC ACID, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Tomasiak, T.M, Archuleta, T.L, Andrell, J, Luna-Chavez, C, Davis, T.A, Sarwar, M, Ham, A.J, McDonald, W.H, Yankowskaya, V, Stern, H.A, Johnston, J.N, Maklashina, E, Cecchini, G, Iverson, T.M.
Deposit date:2010-10-07
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
8SG4
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BU of 8sg4 by Molmil
E1435Q Ycf1 mutant in dephosphorylated state
Descriptor: Metal resistance protein YCF1
Authors:Khandelwal, N.K, Tomasiak, T.M.
Deposit date:2023-04-11
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:E1435Q Ycf1 mutant in dephosphorylated state
To Be Published
7M33
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BU of 7m33 by Molmil
The structure of Bacillus subtilis BmrCD in the inward-facing conformation bound to Hoechst-33342 and ATP
Descriptor: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ...
Authors:Thaker, T.M, Tomasiak, T.M.
Deposit date:2021-03-18
Release date:2022-01-05
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter.
Nat.Chem.Biol., 18, 2022
7M68
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BU of 7m68 by Molmil
E1435Q Ycf1 mutant in inward-facing narrow conformation
Descriptor: Metal resistance protein YCF1
Authors:Khandelwal, N.K, Millan, C.R, Thaker, T.M, Tomasiak, T.M.
Deposit date:2021-03-25
Release date:2022-04-06
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation.
Nat Commun, 13, 2022
7M69
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BU of 7m69 by Molmil
E1435Q Ycf1 mutant in inward-facing wide conformation
Descriptor: Metal resistance protein YCF1
Authors:Khandelwal, N.K, Millan, C.R, Thaker, T.M, Tomasiak, T.M.
Deposit date:2021-03-25
Release date:2022-04-06
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation.
Nat Commun, 13, 2022
4KX6
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BU of 4kx6 by Molmil
Plasticity of the quinone-binding site of the complex II homolog quinol:fumarate reductase
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Singh, P.K, Sarwar, M, Maklashina, E, Kotlyar, V, Rajagukguk, S, Tomasiak, T.M, Cecchini, G, Iverson, T.M.
Deposit date:2013-05-24
Release date:2013-07-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Plasticity of the Quinone-binding Site of the Complex II Homolog Quinol:Fumarate Reductase.
J.Biol.Chem., 288, 2013
5MKK
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BU of 5mkk by Molmil
Crystal structure of the heterodimeric ABC transporter TmrAB, a homolog of the antigen translocation complex TAP
Descriptor: Multidrug resistance ABC transporter ATP-binding and permease protein, SULFATE ION
Authors:Noell, A, Thomas, C, Tomasiak, T.M, Olieric, V, Wang, M, Diederichs, K, Stroud, R.M, Pos, K.M, Tampe, R.
Deposit date:2016-12-05
Release date:2017-01-18
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4LXJ
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BU of 4lxj by Molmil
Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound
Descriptor: LANOSTEROL, Lanosterol 14-alpha demethylase, OXYGEN MOLECULE, ...
Authors:Monk, B.C, Tomasiak, T.M, Keniya, M.V, Huschmann, F.U, Tyndall, J.D.A, O'Connell III, J.D, Cannon, R.D, McDonald, J, Rodriguez, A, Finer-Moore, J, Stroud, R.M.
Deposit date:2013-07-29
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer.
Proc.Natl.Acad.Sci.USA, 111, 2014
5EQB
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BU of 5eqb by Molmil
Crystal structure of lanosterol 14-alpha demethylase with intact transmembrane domain bound to itraconazole
Descriptor: 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Monk, B.C, Tomasiak, T.M, Keniya, M.V, Huschmann, F.U, Tyndall, J.D.A, O'Connell III, J.D, Cannon, R.D, Finer-Morre, J, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
Deposit date:2015-11-12
Release date:2016-01-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer.
Proc.Natl.Acad.Sci.USA, 111, 2014

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