4LXJ

Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound

Summary for 4LXJ

Entry DOI	10.2210/pdb4lxj/pdb
Descriptor	Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, LANOSTEROL, ... (5 entities in total)
Functional Keywords	cytochrome p450, oxidoreductase
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Cellular location	Membrane; Single-pass membrane protein: P10614
Total number of polymer chains	1
Total formula weight	62545.97
Authors	Monk, B.C.,Tomasiak, T.M.,Keniya, M.V.,Huschmann, F.U.,Tyndall, J.D.A.,O'Connell III, J.D.,Cannon, R.D.,McDonald, J.,Rodriguez, A.,Finer-Moore, J.,Stroud, R.M. (deposition date: 2013-07-29, release date: 2014-01-29, Last modification date: 2023-09-20)
Primary citation	Monk, B.C.,Tomasiak, T.M.,Keniya, M.V.,Huschmann, F.U.,Tyndall, J.D.,O'Connell, J.D.,Cannon, R.D.,McDonald, J.G.,Rodriguez, A.,Finer-Moore, J.S.,Stroud, R.M. Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. Proc.Natl.Acad.Sci.USA, 111:3865-3870, 2014 Cited by PubMed: 24613931 DOI: 10.1073/pnas.1324245111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation