4LXJ
Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound
Summary for 4LXJ
Entry DOI | 10.2210/pdb4lxj/pdb |
Descriptor | Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, LANOSTEROL, ... (5 entities in total) |
Functional Keywords | cytochrome p450, oxidoreductase |
Biological source | Saccharomyces cerevisiae (Baker's yeast) |
Cellular location | Membrane; Single-pass membrane protein: P10614 |
Total number of polymer chains | 1 |
Total formula weight | 62545.97 |
Authors | Monk, B.C.,Tomasiak, T.M.,Keniya, M.V.,Huschmann, F.U.,Tyndall, J.D.A.,O'Connell III, J.D.,Cannon, R.D.,McDonald, J.,Rodriguez, A.,Finer-Moore, J.,Stroud, R.M. (deposition date: 2013-07-29, release date: 2014-01-29, Last modification date: 2023-09-20) |
Primary citation | Monk, B.C.,Tomasiak, T.M.,Keniya, M.V.,Huschmann, F.U.,Tyndall, J.D.,O'Connell, J.D.,Cannon, R.D.,McDonald, J.G.,Rodriguez, A.,Finer-Moore, J.S.,Stroud, R.M. Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. Proc.Natl.Acad.Sci.USA, 111:3865-3870, 2014 Cited by PubMed: 24613931DOI: 10.1073/pnas.1324245111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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