7LSW

Structure of Full Beta-Hairpin LIR from FNIP2 Bound to GABARAP

Summary for 7LSW

Entry DOI	10.2210/pdb7lsw/pdb
Descriptor	Folliculin-interacting protein 2,Gamma-aminobutyric acid receptor-associated protein, SULFATE ION (2 entities in total)
Functional Keywords	autophagy, atg8, lir, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	102519.05
Authors	Appleton, B.A. (deposition date: 2021-02-18, release date: 2021-10-13, Last modification date: 2023-10-18)
Primary citation	Goodwin, J.M.,Walkup 4th, W.G.,Hooper, K.,Li, T.,Kishi-Itakura, C.,Ng, A.,Lehmberg, T.,Jha, A.,Kommineni, S.,Fletcher, K.,Garcia-Fortanet, J.,Fan, Y.,Tang, Q.,Wei, M.,Agrawal, A.,Budhe, S.R.,Rouduri, S.R.,Baird, D.,Saunders, J.,Kiselar, J.,Chance, M.R.,Ballabio, A.,Appleton, B.A.,Brumell, J.H.,Florey, O.,Murphy, L.O. GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis. Sci Adv, 7:eabj2485-eabj2485, 2021 Cited by PubMed: 34597140 DOI: 10.1126/sciadv.abj2485 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation