2ANR
 
 | | Crystal structure (II) of Nova-1 KH1/KH2 domain tandem with 25nt RNA hairpin | | Descriptor: | 5'-R(*CP*(5BU)P*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*AP*AP*GP*CP*GP*AP*G)-3', MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Malinina, L, Teplova, M, Musunuru, K, Teplov, A, Darnell, J.C, Burley, S.K, Darnell, R.B, Patel, D.J. | | Deposit date: | 2005-08-11 | | Release date: | 2006-10-24 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
Structure, 19, 2011
|
|
2QCY
 | |
8DS8
 | |
9C8U
 | | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min | | Descriptor: | Isoform 2 of Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ... | | Authors: | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | | Deposit date: | 2024-06-13 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min
To Be Published
|
|
6WW5
 | | Structure of VcINDY-Na-Fab84 in nanodisc | | Descriptor: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, DASS family sodium-coupled anion symporter, Fab84 Heavy Chain, ... | | Authors: | Sauer, D.B, Marden, J, Song, J.M, Koide, A, Koide, S, Wang, D.N. | | Deposit date: | 2020-05-07 | | Release date: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
|
|
5JHM
 | |
5JHL
 | | Crystal structure of zika virus envelope protein in complex with a flavivirus broadly-protective antibody | | Descriptor: | Antibody Heavy chain, antibody Light chain, envelope protein | | Authors: | Dai, L, Shi, Y, Qi, J, Gao, G.F. | | Deposit date: | 2016-04-21 | | Release date: | 2016-05-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody.
Cell Host Microbe, 19, 2016
|
|
6IEC
 | | Structure of RVFV Gn and human monoclonal antibody R17 | | Descriptor: | NSmGnGc, R17 H chain, R17 L chain | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-13 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
|
|
6IEA
 | | Structure of RVFV Gn and human monoclonal antibody R13 | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NSmGnGc, ... | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-13 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
|
|
6IW2
 | | Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state | | Descriptor: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | | Deposit date: | 2018-12-04 | | Release date: | 2019-02-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
|
|
5XOI
 | | The structure of OsALKBH1 | | Descriptor: | MANGANESE (II) ION, Oxidoreductase, 2OG-Fe oxygenase family protein, ... | | Authors: | Wang, C, Guo, Y, Zeng, Z. | | Deposit date: | 2017-05-28 | | Release date: | 2018-06-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Identification and analysis of adenine N6-methylation sites in the rice genome.
Nat Plants, 4, 2018
|
|
6IEK
 | | Structure of RVFV Gn and human monoclonal antibody R12 | | Descriptor: | Heavy chain of Fab R12, Light chain of Fab R12, NSmGnGc | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-14 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
|
|
6IEB
 | | Structure of RVFV Gn and human monoclonal antibody R15 | | Descriptor: | NSmGnGc, R15 H chain, R15 L chain | | Authors: | Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | | Deposit date: | 2018-09-13 | | Release date: | 2019-04-10 | | Last modified: | 2019-07-10 | | Method: | X-RAY DIFFRACTION (2.409 Å) | | Cite: | Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
|
|
6IVZ
 | | Crystal structure of 5A ScFv complexed with YFV-China sE in postfusion state | | Descriptor: | Envelope protein, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | | Deposit date: | 2018-12-04 | | Release date: | 2019-02-13 | | Last modified: | 2019-02-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
|
|
6IW5
 | |
6IW0
 | | Crystal structure of 5A ScFv in complex with YFV-17D sE in postfusion state | | Descriptor: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | | Deposit date: | 2018-12-04 | | Release date: | 2019-02-13 | | Last modified: | 2019-02-27 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
|
|
6IW1
 | |
3CKH
 | | Crystal structure of Eph A4 receptor | | Descriptor: | Ephrin type-A receptor 4 | | Authors: | Shi, J.H, Song, J.X. | | Deposit date: | 2008-03-15 | | Release date: | 2008-09-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor.
J.Biol.Chem., 283, 2008
|
|
6WU2
 | | Structure of the LaINDY-malate complex | | Descriptor: | DASS family sodium-coupled anion symporter, DECANE, HEXANE, ... | | Authors: | Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2020-05-04 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
|
|
6WTW
 | | Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate | | Descriptor: | DASS family sodium-coupled anion symporter | | Authors: | Sauer, D.B, Cocco, N, Marden, J.J, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2020-05-04 | | Release date: | 2020-09-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
|
|
6WU4
 | | Structure of the LaINDY-alpha-ketoglutarate complex | | Descriptor: | DASS family sodium-coupled anion symporter | | Authors: | Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2020-05-04 | | Release date: | 2020-09-16 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
|
|
6WU3
 | |
8ESM
 | | Human triacylglycerol synthesizing enzyme DGAT1 in complex with T863 inhibitor | | Descriptor: | Diacylglycerol O-acyltransferase 1, {(1r,4r)-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl}acetic acid | | Authors: | Sui, X, Kun, W, Walther, T, Farese, R, Liao, M. | | Deposit date: | 2022-10-14 | | Release date: | 2023-06-07 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun, 14, 2023
|
|
8ETM
 | | Human triacylglycerol synthesizing enzyme DGAT1 in complex with DGAT1IN1 inhibitor | | Descriptor: | Diacylglycerol O-acyltransferase 1, [(1S,4r)-4-{4-[(4S)-2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid | | Authors: | Sui, X, Kun, W, Walther, T, Farese, R, Liao, M. | | Deposit date: | 2022-10-17 | | Release date: | 2023-06-07 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun, 14, 2023
|
|
3SXN
 | | Mycobacterium tuberculosis Eis protein initiates modulation of host immune responses by acetylation of DUSP16/MKP-7 | | Descriptor: | COENZYME A, Enhanced intracellular survival protein | | Authors: | Kim, K.H, An, D.R, Yoon, J.Y, Kim, H.S, Yoon, H.J, Song, J.S, Im, H.N, Kim, J, Kim, D.J, Lee, S.J, Kim, H.J, Lee, J.Y, Suh, S.W. | | Deposit date: | 2011-07-15 | | Release date: | 2012-05-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Mycobacterium tuberculosis Eis protein initiates suppression of host immune responses by acetylation of DUSP16/MKP-7
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
