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3CKH

Crystal structure of Eph A4 receptor

Summary for 3CKH
Entry DOI10.2210/pdb3ckh/pdb
Related1NUK 2BBA
DescriptorEphrin type-A receptor 4 (2 entities in total)
Functional Keywordseph receptor, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, transferase, transmembrane, tyrosine-protein kinase
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein: P54764
Total number of polymer chains2
Total formula weight41691.25
Authors
Shi, J.H.,Song, J.X. (deposition date: 2008-03-15, release date: 2008-09-23, Last modification date: 2023-11-01)
Primary citationQin, H.,Shi, J.,Noberini, R.,Pasquale, E.B.,Song, J.
Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor.
J.Biol.Chem., 283:29473-29484, 2008
Cited by
PubMed: 18708347
DOI: 10.1074/jbc.M804114200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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