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5EFM
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BU of 5efm by Molmil
Beclin 1 Flexible-helical Domian (FHD) (141-171)
Descriptor: Beclin-1, SULFATE ION
Authors:Sinha, S, Mei, Y.
Deposit date:2015-10-23
Release date:2016-07-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated Autophagy.
Biochemistry, 55, 2016
6MZ2
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BU of 6mz2 by Molmil
CTX-M-14 Class A Beta-Lactamase in Complex with Avibactam at pH 7.9
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, PHOSPHATE ION, ...
Authors:Pemberton, O.A, Chen, Y.
Deposit date:2018-11-03
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (0.83 Å)
Cite:Mechanism of proton transfer in class A beta-lactamase catalysis and inhibition by avibactam.
Proc.Natl.Acad.Sci.USA, 117, 2020
6MZ1
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BU of 6mz1 by Molmil
CTX-M-14 Class A Beta-Lactamase in Complex with Avibactam at pH 5.3
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, PHOSPHATE ION, ...
Authors:Pemberton, O.A, Chen, Y.
Deposit date:2018-11-03
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1 Å)
Cite:Mechanism of proton transfer in class A beta-lactamase catalysis and inhibition by avibactam.
Proc.Natl.Acad.Sci.USA, 117, 2020
4OB0
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BU of 4ob0 by Molmil
Crystal Structure of Nitrile Hydratase from Pseudonocardia thermophila bound to Phenyl Boronic Acid
Descriptor: COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta, ...
Authors:Rui, W, Salette, M, Ruslan, S, Richard, H, Dali, L.
Deposit date:2014-01-06
Release date:2014-11-26
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile.
J.Am.Chem.Soc., 136, 2014
4OB3
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BU of 4ob3 by Molmil
Crystal Structure of Nitrile Hydratase from Pseudonocardia thermophila : A Reference Structure to Boronic Acid Inhibition of Nitrile Hydratase
Descriptor: COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta, ...
Authors:Rui, W, Salette, M, Ruslan, S, Richard, H, Dali, L.
Deposit date:2014-01-06
Release date:2014-11-26
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile.
J.Am.Chem.Soc., 136, 2014
4OB2
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BU of 4ob2 by Molmil
Crystal Structure of Nitrile Hydratase from Pseudonocardia thermophila bound to Butaneboronic Acid via Crystal Soaking
Descriptor: 1-BUTANE BORONIC ACID, COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, ...
Authors:Rui, W, Salette, M, Ruslan, S, Richard, H, Dali, L.
Deposit date:2014-01-06
Release date:2014-11-26
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile.
J.Am.Chem.Soc., 136, 2014
4OB1
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BU of 4ob1 by Molmil
Crystal Structure of Nitrile Hydratase from Pseudonocardia thermophila bound to Butaneboronic Acid via Co-crystallization
Descriptor: 1-BUTANE BORONIC ACID, COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, ...
Authors:Rui, W, Salette, M, Ruslan, S, Richard, H, Dali, L.
Deposit date:2014-01-06
Release date:2014-11-26
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.631 Å)
Cite:The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile.
J.Am.Chem.Soc., 136, 2014
4UA9
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BU of 4ua9 by Molmil
CTX-M-14 Class A Beta-Lactamase in Complex with a Boronic Acid Acylation Transition State Analog at Sub-Angstrom Resolution
Descriptor: Beta-lactamase CTX-M-14, PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE
Authors:Nichols, D.A, Chen, Y.
Deposit date:2014-08-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.84 Å)
Cite:Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.
J.Am.Chem.Soc., 137, 2015
4UAA
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BU of 4uaa by Molmil
CTX-M-14 Class A Beta-Lactamase in Complex with a Non-Covalent Inhibitor at Sub-Angstrom Resolution
Descriptor: Beta-lactamase CTX-M-14, N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-benzimidazole-4-carboxamide, PHOSPHATE ION
Authors:Nichols, D.A, Chen, Y.
Deposit date:2014-08-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.86 Å)
Cite:Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.
J.Am.Chem.Soc., 137, 2015
4UA6
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BU of 4ua6 by Molmil
CTX-M-14 Class A Beta-Lactamase Apo Crystal Structure at 0.79 Angstrom Resolution
Descriptor: Beta-lactamase CTX-M-14, PHOSPHATE ION, POTASSIUM ION
Authors:Nichols, D.A, Chen, Y.
Deposit date:2014-08-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.79 Å)
Cite:Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.
J.Am.Chem.Soc., 137, 2015
4UA7
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BU of 4ua7 by Molmil
CTX-M-14 Class A Beta-Lactamase in Complex with a Non-Covalent Inhibitor at Sub-Angstrom Resolution
Descriptor: Beta-lactamase CTX-M-14, N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1H-benzimidazole-4-carboxamide, PHOSPHATE ION
Authors:Nichols, D.A, Chen, Y.
Deposit date:2014-08-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.89 Å)
Cite:Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.
J.Am.Chem.Soc., 137, 2015
3L4O
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BU of 3l4o by Molmil
Crystal Structure of the MauG/pre-Methylamine Dehydrogenase Complex After Treatment with Hydrogen Peroxide
Descriptor: ACETATE ION, CALCIUM ION, HEME C, ...
Authors:Jensen, L.M.R, Wilmot, C.M.
Deposit date:2009-12-21
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.046 Å)
Cite:In crystallo posttranslational modification within a MauG/pre-methylamine dehydrogenase complex.
Science, 327, 2010
3L4M
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BU of 3l4m by Molmil
Crystal Structure of the MauG/pre-Methylamine Dehydrogenase Complex.
Descriptor: ACETATE ION, CALCIUM ION, HEME C, ...
Authors:Jensen, L.M.R, Wilmot, C.M.
Deposit date:2009-12-21
Release date:2010-03-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:In crystallo posttranslational modification within a MauG/pre-methylamine dehydrogenase complex.
Science, 327, 2010
5TOP
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BU of 5top by Molmil
Atomic Resolution X-Ray Crystal Structure of a Ruthenocene Conjugated Beta-Lactam Antibiotic in Complex with CTX-M-14 S70G Beta-Lactamase
Descriptor: Beta-lactamase, POTASSIUM ION, RUTHENIUM ION, ...
Authors:Lewandowski, E.M, Chen, Y.
Deposit date:2016-10-18
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Mechanisms of proton relay and product release by Class A beta-lactamase at ultrahigh resolution.
FEBS J., 285, 2018
5TOY
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BU of 5toy by Molmil
X-Ray Crystal Structure of Ruthenocene Conjugated Penicilloate and Penilloate Products in Complex with CTX-M-14 E166A Beta-Lactamase
Descriptor: Beta-lactamase, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Lewandowski, E.M, Chen, Y.
Deposit date:2016-10-19
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Mechanisms of proton relay and product release by Class A beta-lactamase at ultrahigh resolution.
FEBS J., 285, 2018
5VLE
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BU of 5vle by Molmil
Ultrahigh Resolution X-Ray Crystal Structure of Ruthenocene Conjugated Penicilloate and Penilloate Products in Complex with CTX-M-14 E166A Beta-Lactamase
Descriptor: Beta-lactamase, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Lewandowski, E.M, Chen, Y.
Deposit date:2017-04-25
Release date:2017-11-08
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:Mechanisms of proton relay and product release by Class A beta-lactamase at ultrahigh resolution.
FEBS J., 285, 2018
2Q16
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BU of 2q16 by Molmil
Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with ITP
Descriptor: CALCIUM ION, HAM1 protein homolog, INOSINE 5'-TRIPHOSPHATE, ...
Authors:Singer, A.U, Lam, R, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F.
Deposit date:2007-05-23
Release date:2008-02-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.
J.Mol.Biol., 374, 2007
4MI8
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BU of 4mi8 by Molmil
Crystal structure of the complex of murine gamma-herpesvirus 68 Bcl-2 homolog M11 and a Beclin 1 BH3 domain-derived peptide
Descriptor: Bcl-2 homolog (Gene 16?), Beclin-1, SULFATE ION
Authors:Su, M, Mei, Y, Sinha, S.
Deposit date:2013-08-30
Release date:2014-01-29
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting gamma-herpesvirus 68 Bcl-2-mediated down-regulation of autophagy.
J.Biol.Chem., 289, 2014
2PYU
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BU of 2pyu by Molmil
Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with IMP
Descriptor: 1,2-ETHANEDIOL, INOSINIC ACID, Inosine Triphosphate Pyrophosphatase RdgB
Authors:Singer, A.U, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F.
Deposit date:2007-05-16
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.
J.Mol.Biol., 374, 2007
2R8T
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BU of 2r8t by Molmil
Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class II glpX, UNKNOWN ATOM OR ION
Authors:Lunin, V.V, Skarina, T, Brown, G, Yakunin, A, Edwards, A.M, Savchenko, A.
Deposit date:2007-09-11
Release date:2008-08-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate
To be Published
2FPO
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BU of 2fpo by Molmil
Putative methyltransferase yhhF from Escherichia coli.
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, methylase yhhF
Authors:Osipiuk, J, Kim, Y, Sanishvili, R, Skarina, T, Evdokimova, E, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-01-16
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.
J.Biol.Chem., 282, 2007
1LSO
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BU of 1lso by Molmil
Crystal Structure of the S137A mutant of L-3-Hydroxyacyl-CoA Dehydrogenase in Complex with NAD
Descriptor: 3-HYDROXYACYL-COA DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Barycki, J.J, Banaszak, L.J.
Deposit date:2002-05-17
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the S137A mutant of L-3-Hydroxyacyl-CoA Dehydrogenase in Complex with NAD
To be Published
1LSJ
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BU of 1lsj by Molmil
Crystal Structure of the E110Q Mutant of L-3-Hydroxyacyl-CoA Dehydrogenase in Complex with NAD
Descriptor: 3-HYDROXYACYL-COA DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Barycki, J.J, Banaszak, L.J.
Deposit date:2002-05-17
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the E110Q Mutant of L-3-Hydroxyacyl-CoA Dehydrogenase in Complex with NAD
To be Published
1F14
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BU of 1f14 by Molmil
L-3-HYDROXYACYL-COA DEHYDROGENASE (APO)
Descriptor: L-3-HYDROXYACYL-COA DEHYDROGENASE
Authors:Barycki, J.J, O'Brien, L.K, Strauss, A.W, Banaszak, L.J.
Deposit date:2000-05-18
Release date:2000-09-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase.
J.Biol.Chem., 275, 2000
1F0Y
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BU of 1f0y by Molmil
L-3-HYDROXYACYL-COA DEHYDROGENASE COMPLEXED WITH ACETOACETYL-COA AND NAD+
Descriptor: ACETOACETYL-COENZYME A, L-3-HYDROXYACYL-COA DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Barycki, J.J, O'Brien, L.K, Strauss, A.W, Banaszak, L.J.
Deposit date:2000-05-17
Release date:2000-09-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase.
J.Biol.Chem., 275, 2000

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