5EFM

Beclin 1 Flexible-helical Domian (FHD) (141-171)

Summary for 5EFM

• Entry DOI: 10.2210/pdb5efm/pdb
• Descriptor: Beclin-1, SULFATE ION (3 entities in total)
• Functional Keywords: flexible helix, apoptosis
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm . Beclin-1-C 35 kDa: Mitochondrion . Beclin-1-C 37 kDa: Mitochondrion : Q14457
• Total number of polymer chains: 1
• Total formula weight: 3782.10

Authors

Sinha, S.,Mei, Y. (deposition date: 2015-10-23, release date: 2016-07-20, Last modification date: 2017-11-22)

• Primary citation: Mei, Y.,Ramanathan, A.,Glover, K.,Stanley, C.,Sanishvili, R.,Chakravarthy, S.,Yang, Z.,Colbert, C.L.,Sinha, S.C.; Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated Autophagy.; Biochemistry, 55:1945-1958, 2016; PubMed: 26937551; DOI: 10.1021/acs.biochem.5b01264

Experimental method

X-RAY DIFFRACTION (1.95 Å)