5TOY
X-Ray Crystal Structure of Ruthenocene Conjugated Penicilloate and Penilloate Products in Complex with CTX-M-14 E166A Beta-Lactamase
Summary for 5TOY
Entry DOI | 10.2210/pdb5toy/pdb |
Related PRD ID | PRD_900003 |
Descriptor | Beta-lactamase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, POTASSIUM ION, ... (8 entities in total) |
Functional Keywords | beta-lactamase, organometallic, ruthenocene, ctx-m-14, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 59537.11 |
Authors | Lewandowski, E.M.,Chen, Y. (deposition date: 2016-10-19, release date: 2017-11-08, Last modification date: 2023-10-04) |
Primary citation | Lewandowski, E.M.,Lethbridge, K.G.,Sanishvili, R.,Skiba, J.,Kowalski, K.,Chen, Y. Mechanisms of proton relay and product release by Class A beta-lactamase at ultrahigh resolution. FEBS J., 285:87-100, 2018 Cited by PubMed: 29095570DOI: 10.1111/febs.14315 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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