2PYU

Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with IMP

Summary for 2PYU

Entry DOI	10.2210/pdb2pyu/pdb
Related	1K7K 2Q16
Descriptor	Inosine Triphosphate Pyrophosphatase RdgB, INOSINIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	itp pyrophosphatase x-ray structure enzyme mechanism product, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	23745.57
Authors	Singer, A.U.,Proudfoot, M.,Skarina, T.,Savchenko, A.,Yakunin, A.F. (deposition date: 2007-05-16, release date: 2008-03-18, Last modification date: 2023-08-30)
Primary citation	Savchenko, A.,Proudfoot, M.,Skarina, T.,Singer, A.,Litvinova, O.,Sanishvili, R.,Brown, G.,Chirgadze, N.,Yakunin, A.F. Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374:1091-1103, 2007 Cited by PubMed: 17976651 DOI: 10.1016/j.jmb.2007.10.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.02 Å)

Structure validation