2PYU

Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with IMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Inosine Triphosphate Pyrophosphatase RdgB	polymer	219	23335.3	1	UniProt (P52061) Pfam (PF01725)	Escherichia coli
2	B (A)	INOSINIC ACID	non-polymer		348.2	1	Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734)
3	C (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	D (A)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A: 1 - 197 (UniProt: P52061)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ala 69	Asp 69	engineered mutation
Gly 198	-	expression tag
Ser 199	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23335.3
Non-Polymers*	Number of molecules	2
	Total formula weight	410.3
All*	Total formula weight	23745.6

*Water molecules are not included.