2PYU
Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with IMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0009143 | biological_process | nucleoside triphosphate catabolic process |
| A | 0009146 | biological_process | purine nucleoside triphosphate catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017111 | molecular_function | ribonucleoside triphosphate phosphatase activity |
| A | 0035870 | molecular_function | dITP diphosphatase activity |
| A | 0036220 | molecular_function | ITP diphosphatase activity |
| A | 0036222 | molecular_function | XTP diphosphatase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047429 | molecular_function | nucleoside triphosphate diphosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE IMP A 3036 |
| Chain | Residue |
| A | SER70 |
| A | HIS182 |
| A | HOH3067 |
| A | HOH3074 |
| A | HOH3106 |
| A | GLY71 |
| A | SER85 |
| A | ALA86 |
| A | PHE118 |
| A | PHE154 |
| A | TYR156 |
| A | ASP157 |
| A | LYS177 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 600 |
| Chain | Residue |
| A | PRO81 |
| A | GLY82 |
| A | ILE83 |
| A | HOH3040 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"17976651","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01405","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17976651","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2Q16","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01405","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17976651","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2Q16","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
