6GSN
 
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6GSM
 | | Structure of a partial yeast 48S preinitiation complex in open conformation. | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | | 著者 | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2018-06-14 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | | 主引用文献 | Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
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2JJ4
 | | The complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC7942 | | 分子名称: | ACETYLGLUTAMATE KINASE, N-ACETYL-L-GLUTAMATE, NITROGEN REGULATORY PROTEIN P-II | | 著者 | Llacer, J.L, Marco-Marin, C, Gil-Ortiz, F, Fita, I, Rubio, V. | | 登録日 | 2007-07-04 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | The Crystal Structure of the Complex of Pii and Acetylglutamate Kinase Reveals How Pii Controls the Storage of Nitrogen as Arginine
Proc.Natl.Acad.Sci.USA, 104, 2007
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2V5H
 | | Controlling the storage of nitrogen as arginine: the complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC 7942 | | 分子名称: | ACETYLGLUTAMATE KINASE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Llacer, J.L, Marco-Marin, C, Gil-Ortiz, F, Fita, I, Rubio, V. | | 登録日 | 2007-07-04 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | The Crystal Structure of the Complex of Pii and Acetylglutamate Kinase Reveals How Pii Controls the Storage of Nitrogen as Arginine.
Proc.Natl.Acad.Sci.USA, 104, 2007
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2XGX
 | | Crystal structure of transcription factor NtcA from Synechococcus elongatus (mercury derivative) | | 分子名称: | 2-OXOGLUTARIC ACID, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLOBAL NITROGEN REGULATOR, ... | | 著者 | Llacer, J.L, Castells, M.A, Rubio, V. | | 登録日 | 2010-06-08 | | 公開日 | 2010-08-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2XKO
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2XG8
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2XKP
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2XHK
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6FYX
 | | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | | 著者 | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2018-03-12 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
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6FYY
 | | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | | 著者 | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2018-03-12 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
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3JAM
 | | CryoEM structure of 40S-eIF1A-eIF1 complex from yeast | | 分子名称: | 18S rRNA, MAGNESIUM ION, RACK1, ... | | 著者 | Llacer, J.L, Hussain, T, Ramakrishnan, V. | | 登録日 | 2015-06-17 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
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3JAP
 | | Structure of a partial yeast 48S preinitiation complex in closed conformation | | 分子名称: | 18S rRNA, MAGNESIUM ION, METHIONINE, ... | | 著者 | Llacer, J.L, Hussain, T, Ramakrishnan, V. | | 登録日 | 2015-06-18 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
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6QG1
 | | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2) | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | | 著者 | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
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2JER
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6QG6
 | | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D) | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | | 著者 | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.65 Å) | | 主引用文献 | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
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6QG2
 | | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model A) | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | | 著者 | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
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6QG0
 | | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1) | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | | 著者 | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
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6QG3
 | | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B) | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | | 著者 | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
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6QG5
 | | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C) | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | | 著者 | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (10.1 Å) | | 主引用文献 | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
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8P99
 | | SARS-CoV-2 S-protein:D614G mutant in 1-up conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1,Spike glycoprotein | | 著者 | Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L. | | 登録日 | 2023-06-05 | | 公開日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
J.Med.Chem., 66, 2023
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8P9Y
 | | SARS-CoV-2 S protein S:D614G mutant in 3-down with binding site of an entry inhibitor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | | 著者 | Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L. | | 登録日 | 2023-06-06 | | 公開日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
J.Med.Chem., 66, 2023
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7QDG
 | | SARS-CoV-2 S protein S:A222V + S:D614G mutant 1-up | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M. | | 登録日 | 2021-11-27 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation.
Plos Pathog., 18, 2022
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7QDH
 | | SARS-CoV-2 S protein S:D614G mutant 1-up | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | | 著者 | Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M. | | 登録日 | 2021-11-27 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation.
Plos Pathog., 18, 2022
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4OZN
 | | GlnK2 from Haloferax mediterranei complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Nitrogen regulatory protein P-II, SULFATE ION | | 著者 | Palanca, C, Pedro-Roig, L, Llacer, J.L, Camacho, M, Bonete, M.J, Rubio, V. | | 登録日 | 2014-02-17 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high-salt adaptations.
Febs J., 281, 2014
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