Structure of a partial yeast 48S preinitiation complex in open conformation

This is a large structure.
Replaces:  3JAQ

Summary for 6GSM

Related3JAP 3JAQ
EMDB information3048 3049 0057
DescriptorMet-tRNAi, 18S ribosomal RNA, 40S ribosomal protein S0, ... (51 entities in total)
Functional Keywordsribosome, translation, initiation factors, 40s, eif1a, eif3, eif2, trnai, 48s pic, small ribosome subunit
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Total number of polymer chains47
Total molecular weight1537168.49
Llacer, J.L.,Hussain, T.,Gordiyenko, Y.,Ramakrishnan, V. (deposition date: 2018-06-14, release date: 2019-07-31)
Primary citation
Llacer, J.L.,Hussain, T.,Gordiyenko, Y.,Ramakrishnan, V.
Towards a model of eIF3 on the 40S subunit interface in eukaryotic translation initiation
To Be Published,
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone4 3.6% 10.8% 0.32MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures