6QG1

Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2)

Summary for 6QG1

• Entry DOI: 10.2210/pdb6qg1/pdb
• Related: 6QG0
• EMDB information: 4543 4544
• Descriptor: Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ... (8 entities in total)
• Functional Keywords: integrated stress response, isr, translation, initiation factors, phosphorylation, eif2, eif2b, trnai, gef, heat domain, eif2 alpha
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 16
• Total formula weight: 838127.37

Authors

Llacer, J.L.,Gordiyenko, Y.,Ramakrishnan, V. (deposition date: 2019-01-10, release date: 2019-06-26, Last modification date: 2019-12-18)

• Primary citation: Gordiyenko, Y.,Llacer, J.L.,Ramakrishnan, V.; Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.; Nat Commun, 10:2640-2640, 2019; PubMed: 31201334; DOI: 10.1038/s41467-019-10606-1

Experimental method

ELECTRON MICROSCOPY (4.2 Å)