7BZ4
 
 | |
7BYQ
 | |
7BZ1
 | |
7BZI
 | |
7BZ3
 | |
2WZZ
 | |
2WZX
 | |
7V6E
 | | DREP3 | | Descriptor: | DNAation factor-related protein 3, isoform A | | Authors: | Lee, S.Y, Park, H.H. | | Deposit date: | 2021-08-20 | | Release date: | 2022-08-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Helical filament structure of the DREP3 CIDE domain reveals a unified mechanism of CIDE-domain assembly.
Acta Crystallogr D Struct Biol, 77, 2021
|
|
7DHA
 | | crystal structure of CD38 in complex with daratumumab | | Descriptor: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy Chain, Light chain | | Authors: | Lee, H.T, Heo, Y.S. | | Deposit date: | 2020-11-13 | | Release date: | 2021-09-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure of CD38 in complex with daratumumab, a first-in-class anti-CD38 antibody drug for treating multiple myeloma.
Biochem.Biophys.Res.Commun., 536, 2021
|
|
3V6A
 | |
5D8D
 | |
5DMX
 | |
8K3Y
 | | The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | Authors: | Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I. | | Deposit date: | 2023-07-17 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (4.42 Å) | | Cite: | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
|
|
7VG5
 | | 10,5-methenyltetrahydrofolate cyclohydrolase from Methylobacterium extorquens AM1 with tetrahydrofolate | | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, Methenyltetrahydrofolate cyclohydrolase | | Authors: | Kim, S, Lee, S, Kim, I.-K, Seo, H, Kim, K.-J. | | Deposit date: | 2021-09-14 | | Release date: | 2022-07-06 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural insight into a molecular mechanism of methenyltetrahydrofolate cyclohydrolase from Methylobacterium extorquens AM1.
Int.J.Biol.Macromol., 202, 2022
|
|
7VG4
 | | 10,5-methenyltetrahydrofolate cyclohydrolase from Methylobacterium extorquens AM1 strain | | Descriptor: | Methenyltetrahydrofolate cyclohydrolase | | Authors: | Kim, S, Lee, S, Kim, I.-K, Seo, H, Kim, K.-J. | | Deposit date: | 2021-09-14 | | Release date: | 2022-07-06 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Structural insight into a molecular mechanism of methenyltetrahydrofolate cyclohydrolase from Methylobacterium extorquens AM1.
Int.J.Biol.Macromol., 202, 2022
|
|
7C11
 | | Formate--tetrahydrofolate ligase from Methylobacterium extorquens CM4 strain | | Descriptor: | ACETATE ION, CITRATE ANION, Formate-tetrahydrofolate ligase, ... | | Authors: | Kim, K.-J, Kim, S, Seo, H, Lee, S. | | Deposit date: | 2020-05-02 | | Release date: | 2020-10-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.815 Å) | | Cite: | Biochemical properties and crystal structure of formate-tetrahydrofolate ligase from Methylobacterium extorquens CM4.
Biochem.Biophys.Res.Commun., 528, 2020
|
|
6JC2
 | | Crystal structure of the Fab fragment of ipilimumab | | Descriptor: | SULFATE ION, ipilimumab fab heavy chain, ipilimumab fab light chain | | Authors: | Heo, Y.S. | | Deposit date: | 2019-01-27 | | Release date: | 2019-09-11 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal Structure of the Fab Fragment of an Anti-CTLA-4 Antibody, Ipilimumab, Used for Cancer Immunotherapy
Bull.Korean Chem.Soc., 40, 2019
|
|
6J52
 | | Crystal structure of CARD-only protein in frog virus 3 | | Descriptor: | Caspase recruitment domain-only protein | | Authors: | Park, H.H, Kwon, S. | | Deposit date: | 2019-01-10 | | Release date: | 2019-02-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.504 Å) | | Cite: | Structural transformation-mediated dimerization of caspase recruitment domain revealed by the crystal structure of CARD-only protein in frog virus 3.
J. Struct. Biol., 205, 2019
|
|
6K8H
 | | Crystal structure of an omega-transaminase from Sphaerobacter thermophilus | | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Aminotransferase class-III | | Authors: | Park, H.H, Kwon, S. | | Deposit date: | 2019-06-12 | | Release date: | 2019-10-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural insights into the enzyme specificity of a novel omega-transaminase from the thermophilic bacterium Sphaerobacter thermophilus.
J.Struct.Biol., 208, 2019
|
|
7F3V
 | | Crystal structure of YfiH with C107A mutation in complex with endogenous UDP-MurNAc | | Descriptor: | (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ... | | Authors: | Lee, M.S, Hsieh, K.Y, Chang, C.I. | | Deposit date: | 2021-06-17 | | Release date: | 2021-12-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Structural Basis for the Peptidoglycan-Editing Activity of YfiH.
Mbio, 13, 2021
|
|
4RX5
 | | Bruton's tyrosine kinase (BTK) with pyridazinone compound 23 | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, GLYCEROL, N-(6-fluoro-2-methyl-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl)-1-benzothiophene-2-carboxamide, ... | | Authors: | Eigenbrot, C, Yu, C. | | Deposit date: | 2014-12-08 | | Release date: | 2015-12-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.356 Å) | | Cite: | Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability.
Bioorg.Med.Chem.Lett., 26, 2016
|
|
3K9K
 | | Transposase domain of Metnase | | Descriptor: | Histone-lysine N-methyltransferase SETMAR | | Authors: | Goodwin, K.D, He, H, Imasaki, T, Lee, S.-H, Georgiadis, M.M. | | Deposit date: | 2009-10-15 | | Release date: | 2010-07-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure of the human Hsmar1-derived transposase domain in the DNA repair enzyme Metnase.
Biochemistry, 49, 2010
|
|
4DXD
 | | Staphylococcal Aureus FtsZ in complex with 723 | | Descriptor: | 3-[(6-chloro[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Lu, J, Soisson, S.M. | | Deposit date: | 2012-02-27 | | Release date: | 2012-05-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics.
Sci Transl Med, 4, 2012
|
|
3K9J
 | | Transposase domain of Metnase | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Histone-lysine N-methyltransferase SETMAR | | Authors: | Goodwin, K.D, He, H, Imasaki, T, Lee, S.-H, Georgiadis, M.M. | | Deposit date: | 2009-10-15 | | Release date: | 2010-07-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.903 Å) | | Cite: | Crystal structure of the human Hsmar1-derived transposase domain in the DNA repair enzyme Metnase.
Biochemistry, 49, 2010
|
|
3L6Y
 | | Crystal structure of p120 catenin in complex with E-cadherin | | Descriptor: | Catenin delta-1, E-cadherin | | Authors: | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | | Deposit date: | 2009-12-27 | | Release date: | 2010-04-21 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Cell(Cambridge,Mass.), 141, 2010
|
|
