4DXD

Staphylococcal Aureus FtsZ in complex with 723

Summary for 4DXD

• Entry DOI: 10.2210/pdb4dxd/pdb
• Descriptor: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, 3-[(6-chloro[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide, ... (4 entities in total)
• Functional Keywords: rossmann fold, gtpase, gtp binding, cell cycle-inhibitor complex, cell cycle/inhibitor
• Biological source: Staphylococcus aureus
• Cellular location: Cytoplasm (By similarity): P0A031
• Total number of polymer chains: 1
• Total formula weight: 42706.63

Authors

Lu, J.,Soisson, S.M. (deposition date: 2012-02-27, release date: 2012-05-23, Last modification date: 2024-02-28)

• Primary citation: Tan, C.M.,Therien, A.G.,Lu, J.,Lee, S.H.,Caron, A.,Gill, C.J.,Lebeau-Jacob, C.,Benton-Perdomo, L.,Monteiro, J.M.,Pereira, P.M.,Elsen, N.L.,Wu, J.,Deschamps, K.,Petcu, M.,Wong, S.,Daigneault, E.,Kramer, S.,Liang, L.,Maxwell, E.,Claveau, D.,Vaillancourt, J.,Skorey, K.,Tam, J.,Wang, H.,Meredith, T.C.,Sillaots, S.,Wang-Jarantow, L.,Ramtohul, Y.,Langlois, E.,Landry, F.,Reid, J.C.,Parthasarathy, G.,Sharma, S.,Baryshnikova, A.,Lumb, K.J.,Pinho, M.G.,Soisson, S.M.,Roemer, T.; Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics.; Sci Transl Med, 4:126ra35-126ra35, 2012; PubMed: 22440737; DOI: 10.1126/scitranslmed.3003592

Experimental method

X-RAY DIFFRACTION (2.01 Å)