2WZX
AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA)IN COMPLEX WITH compound M-02
Summary for 2WZX
Entry DOI | 10.2210/pdb2wzx/pdb |
Related | 2WZZ |
Descriptor | BETA-LACTAMASE, (3R)-1-[(4S)-azepan-4-ylcarbamoyl]-3-(sulfoamino)-L-proline, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | inhibitor, hydrolase, antibiotic resistance |
Biological source | PSEUDOMONAS AERUGINOSA |
Cellular location | Periplasm (By similarity): P24735 |
Total number of polymer chains | 1 |
Total formula weight | 41109.81 |
Authors | Fitzgerald, P.M.D.,Sharma, N.,Lu, J. (deposition date: 2009-12-03, release date: 2010-01-12, Last modification date: 2011-07-13) |
Primary citation | Blizzard, T.A.,Chen, H.,Kim, S.,Wu, J.,Young, K.,Park, Y.,Ogawa, A.,Raghoobar, S.,Painter, R.E.,Hairston, N.,Lee, S.H.,Misura, A.,Felcetto, T.,Fitzgerald, P.M.D.,Sharma, N.,Lu, J.,Ha, S.,Hickey, E.,Hermes, J.,Hammond, M.L. Side Chain Sar of Bicyclic Beta-Lactamase Inhibitors (Blis). 1. Discovery of a Class C Bli for Combination with Imipinem. Bioorg.Med.Chem.Lett., 20:918-, 2010 Cited by PubMed: 20044254DOI: 10.1016/J.BMCL.2009.12.069 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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