6JC2

Crystal structure of the Fab fragment of ipilimumab

Summary for 6JC2

• Entry DOI: 10.2210/pdb6jc2/pdb
• Descriptor: ipilimumab fab heavy chain, ipilimumab fab light chain, SULFATE ION, ... (4 entities in total)
• Functional Keywords: ipilimumab, ctla-4, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 48756.13

Authors

Heo, Y.S. (deposition date: 2019-01-27, release date: 2019-09-11)

• Primary citation: Lee, J.Y.,Lee, H.T.,Lee, S.H.,Lim, H.,Heo, Y.S.; Crystal Structure of the Fab Fragment of an Anti-CTLA-4 Antibody, Ipilimumab, Used for Cancer Immunotherapy; Bull.Korean Chem.Soc., 40:582-585, 2019; DOI: 10.1002/bkcs.11712

Experimental method

X-RAY DIFFRACTION (2.65 Å)