7DHA
crystal structure of CD38 in complex with daratumumab
Summary for 7DHA
Entry DOI | 10.2210/pdb7dha/pdb |
Descriptor | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Light chain, Heavy Chain, ... (4 entities in total) |
Functional Keywords | cd38, antibody, daratumumab, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 79130.75 |
Authors | |
Primary citation | Lee, H.T.,Kim, Y.,Park, U.B.,Jeong, T.J.,Lee, S.H.,Heo, Y.S. Crystal structure of CD38 in complex with daratumumab, a first-in-class anti-CD38 antibody drug for treating multiple myeloma. Biochem.Biophys.Res.Commun., 536:26-31, 2021 Cited by PubMed: 33360095DOI: 10.1016/j.bbrc.2020.12.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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