7BZ3

The mutant variant of PNGM-1. H257 was substituted for alanine to study substrate binding.

Summary for 7BZ3

• Entry DOI: 10.2210/pdb7bz3/pdb
• Related: 6j4n
• Descriptor: Metallo-beta-lactamase PNGM-1, ZINC ION (3 entities in total)
• Functional Keywords: rnase z, mbls, carbapenemase, antibiotic
• Biological source: uncultured bacterium
• Total number of polymer chains: 4
• Total formula weight: 167061.10

Authors

Park, Y.S.,Kang, L.W.,Lee, J.H. (deposition date: 2020-04-26, release date: 2021-04-28, Last modification date: 2024-03-27)

• Primary citation: Park, Y.S.,Kim, T.Y.,Park, H.,Lee, J.H.,Nguyen, D.Q.,Hong, M.K.,Lee, S.H.,Kang, L.W.; Structural Study of Metal Binding and Coordination in Ancient Metallo-beta-Lactamase PNGM-1 Variants.; Int J Mol Sci, 21:-, 2020; PubMed: 32664695; DOI: 10.3390/ijms21144926

Experimental method

X-RAY DIFFRACTION (2 Å)