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3CDZ
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BU of 3cdz by Molmil
Crystal structure of human factor VIII
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Ngo, J.C, Huang, M, Roth, D.A, Furie, B.C, Furie, B.
登録日2008-02-27
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex.
Structure, 16, 2008
4XSK
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BU of 4xsk by Molmil
Structure of PAItrap, an uPA mutant
分子名称: GLYCEROL, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Gong, L, Proulle, V, Hong, Z, Lin, Z, Liu, M, Yuan, C, Lin, L, Furie, B, Flaumenhaft, R, Andreasen, P, Furie, B, Huang, M.
登録日2015-01-22
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of PAItrap, an uPA mutant
To Be Published
1WCT
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BU of 1wct by Molmil
A NOVEL CONOTOXIN FROM CONUS TEXTILE WITH UNUSUAL POST-TRANSLATIONAL MODIFICATIONS REDUCES PRESYNAPTIC CALCIUM INFLUX, NMR, 1 STRUCTURE, GLYCOSYLATED PROTEIN
分子名称: OMEGAC-TXIX, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose
著者Rigby, A.C, Hambe, B, Czerwiec, E, Baleja, J.D, Furie, B.C, Furie, B, Stenflo, J.
登録日1998-12-18
公開日1999-06-08
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献A conotoxin from Conus textile with unusual posttranslational modifications reduces presynaptic Ca2+ influx.
Proc.Natl.Acad.Sci.USA, 96, 1999
1AD7
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BU of 1ad7 by Molmil
NMR STRUCTURE OF METAL-FREE CONANTOKIN G, 1 STRUCTURE
分子名称: CONANTOXIN G
著者Rigby, A.C, Baleja, J.D, Furie, B.C, Furie, B.
登録日1997-02-21
公開日1997-08-20
最終更新日2015-10-21
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of a gamma-carboxyglutamic acid-containing conotoxin, conantokin G, from the marine snail Conus geographus: the metal-free conformer.
Biochemistry, 36, 1997
1AWY
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BU of 1awy by Molmil
NMR STRUCTURE OF CALCIUM BOUND CONFORMER OF CONANTOKIN G, MINIMIZED AVERAGE STRUCTURE
分子名称: CONANTOXIN G
著者Rigby, A.C, Baleja, J.D, Leping, L, Pedersen, L.G, Furie, B.C, Furie, B.
登録日1997-10-06
公開日1998-04-08
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Role of gamma-carboxyglutamic acid in the calcium-induced structural transition of conantokin G, a conotoxin from the marine snail Conus geographus.
Biochemistry, 36, 1997
1NL0
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BU of 1nl0 by Molmil
Crystal structure of human factor IX Gla domain in complex of an inhibitory antibody, 10C12
分子名称: CALCIUM ION, SULFATE ION, anti-factor IX antibody, ...
著者Huang, M, Furie, B.C, Furie, B.
登録日2003-01-06
公開日2004-01-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Calcium-stabilized Human Factor IX Gla Domain Bound to a Conformation-specific Anti-factor IX Antibody.
J.Biol.Chem., 279, 2004
1NL1
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BU of 1nl1 by Molmil
BOVINE PROTHROMBIN FRAGMENT 1 IN COMPLEX WITH CALCIUM ION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huang, M, Huang, G, Furie, B, Seaton, B, Furie, B.C.
登録日2003-01-06
公開日2003-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins.
Nat.Struct.Biol., 10, 2003
1NL2
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BOVINE PROTHROMBIN FRAGMENT 1 IN COMPLEX WITH CALCIUM AND LYSOPHOSPHOTIDYLSERINE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huang, M, Huang, G, Furie, B, Seaton, B, Furie, B.C.
登録日2003-01-06
公開日2003-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins.
Nat.Struct.Biol., 10, 2003
1CFI
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BU of 1cfi by Molmil
NMR STRUCTURE OF CALCIUM ION-BOUND GAMMA-CARBOXY-GLUTAMIC ACID-RICH DOMAIN OF FACTOR IX
分子名称: COAGULATION FACTOR IX
著者Freedman, S.J, Furie, B.C, Furie, B, Baleja, J.D.
登録日1995-04-26
公開日1996-06-20
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structure of the calcium ion-bound gamma-carboxyglutamic acid-rich domain of factor IX.
Biochemistry, 34, 1995
1FSB
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BU of 1fsb by Molmil
STRUCTURE OF THE EGF DOMAIN OF P-SELECTIN, NMR, 19 STRUCTURES
分子名称: P-SELECTIN
著者Freedman, S.J, Sanford, D.G, Bachovchin, W.W, Furie, B.C, Baleja, J.D, Furie, B.
登録日1996-03-25
公開日1997-04-01
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Structure and function of the epidermal growth factor domain of P-selectin.
Biochemistry, 35, 1996
1CFH
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BU of 1cfh by Molmil
STRUCTURE OF THE METAL-FREE GAMMA-CARBOXYGLUTAMIC ACID-RICH MEMBRANE BINDING REGION OF FACTOR IX BY TWO-DIMENSIONAL NMR SPECTROSCOPY
分子名称: COAGULATION FACTOR IX, FORMIC ACID
著者Freedman, S.J, Furie, B.C, Furie, B, Baleja, J.D.
登録日1995-02-26
公開日1995-07-10
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Structure of the metal-free gamma-carboxyglutamic acid-rich membrane binding region of factor IX by two-dimensional NMR spectroscopy.
J.Biol.Chem., 270, 1995
1MGX
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BU of 1mgx by Molmil
COAGULATION FACTOR, MG(II), NMR, 7 STRUCTURES (BACKBONE ATOMS ONLY)
分子名称: COAGULATION FACTOR IX
著者Freedman, S.J, Furie, B.C, Furie, B, Baleja, J.D.
登録日1995-06-21
公開日1996-11-08
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Identification of the phospholipid binding site in the vitamin K-dependent blood coagulation protein factor IX.
J.Biol.Chem., 271, 1996
2PQS
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BU of 2pqs by Molmil
Crystal Structure of the Bovine Lactadherin C2 Domain
分子名称: Lactadherin
著者Huang, M, Furie, B.C.
登録日2007-05-02
公開日2007-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the bovine lactadherin C2 domain, a membrane binding motif, shows similarity to the C2 domains of factor V and factor VIII.
J.Mol.Biol., 371, 2007
3PB1
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BU of 3pb1 by Molmil
Crystal Structure of a Michaelis Complex between Plasminogen Activator Inhibitor-1 and Urokinase-type Plasminogen Activator
分子名称: Plasminogen activator inhibitor 1, Plasminogen activator, urokinase, ...
著者Lin, Z, Jiang, L, Huang, M, Structure 2 Function Project (S2F)
登録日2010-10-20
公開日2010-12-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1.
J.Biol.Chem., 286, 2011
2FD6
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BU of 2fd6 by Molmil
Structure of Human Urokinase Plasminogen Activator in Complex with Urokinase Receptor and an anti-upar antibody at 1.9 A
分子名称: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ...
著者Huang, M, Huai, Q, Li, Y.
登録日2005-12-13
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of human urokinase plasminogen activator in complex with its receptor
Science, 311, 2006
3BT1
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Structure of urokinase receptor, urokinase and vitronectin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ...
著者Huang, M.
登録日2007-12-27
公開日2008-03-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3BT2
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Structure of urokinase receptor, urokinase and vitronectin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ...
著者Huang, M.
登録日2007-12-27
公開日2008-03-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Nat.Struct.Mol.Biol., 15, 2008
3HNB
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Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
分子名称: (2R)-1-(2,4-dichlorophenoxy)-3-[(2E)-2-imino-3-(2-piperidin-1-ylethyl)-2,3-dihydro-1H-benzimidazol-1-yl]propan-2-ol, Coagulation factor VIII
著者Liu, Z, Yuan, C.
登録日2009-05-31
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding.
J.Biol.Chem., 285, 2010
3HNY
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Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
分子名称: Coagulation factor VIII
著者Liu, Z, Yuan, C.
登録日2009-06-01
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding.
J.Biol.Chem., 285, 2010
3HOB
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Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
分子名称: Coagulation factor VIII
著者Liu, Z, Yuan, C.
登録日2009-06-01
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding.
J.Biol.Chem., 285, 2010
4O03
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Crystal structure of Ca2+ bound prothrombin deletion mutant residues 146-167
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Prothrombin
著者Pozzi, N, Chen, Z, Shropshire, D.B, Pelc, L.A, Di Cera, E.
登録日2013-12-13
公開日2014-05-21
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献The linker connecting the two kringles plays a key role in prothrombin activation.
Proc.Natl.Acad.Sci.USA, 111, 2014

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