3CDZ

Crystal structure of human factor VIII

Summary for 3CDZ

• Entry DOI: 10.2210/pdb3cdz/pdb
• Descriptor: Coagulation factor VIII heavy chain, Coagulation factor VIII light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: blood clotting, blood coagulation, cofactor, factor viii, refacto, acute phase, disease mutation, glycoprotein, hemophilia, metal-binding, secreted, sulfation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 167247.95

Authors

Ngo, J.C.,Huang, M.,Roth, D.A.,Furie, B.C.,Furie, B. (deposition date: 2008-02-27, release date: 2008-04-01, Last modification date: 2023-08-30)

• Primary citation: Ngo, J.C.,Huang, M.,Roth, D.A.,Furie, B.C.,Furie, B.; Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex.; Structure, 16:597-606, 2008; PubMed: 18400180; DOI: 10.1016/j.str.2008.03.001

Experimental method

X-RAY DIFFRACTION (3.98 Å)