1WCT

A NOVEL CONOTOXIN FROM CONUS TEXTILE WITH UNUSUAL POST-TRANSLATIONAL MODIFICATIONS REDUCES PRESYNAPTIC CALCIUM INFLUX, NMR, 1 STRUCTURE, GLYCOSYLATED PROTEIN

Summary for 1WCT

Entry DOI	10.2210/pdb1wct/pdb
Descriptor	OMEGAC-TXIX, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose (2 entities in total)
Functional Keywords	gamma-carboxy glutamic acid, novel omega conotoxin, calcium channel blocker
Biological source	Conus textile (cloth-of-gold cone)
Cellular location	Secreted: P81755
Total number of polymer chains	1
Total formula weight	1953.80
Authors	Rigby, A.C.,Hambe, B.,Czerwiec, E.,Baleja, J.D.,Furie, B.C.,Furie, B.,Stenflo, J. (deposition date: 1998-12-18, release date: 1999-06-08, Last modification date: 2020-07-29)
Primary citation	Rigby, A.C.,Lucas-Meunier, E.,Kalume, D.E.,Czerwiec, E.,Hambe, B.,Dahlqvist, I.,Fossier, P.,Baux, G.,Roepstorff, P.,Baleja, J.D.,Furie, B.C.,Furie, B.,Stenflo, J. A conotoxin from Conus textile with unusual posttranslational modifications reduces presynaptic Ca2+ influx. Proc.Natl.Acad.Sci.USA, 96:5758-5763, 1999 Cited by PubMed: 10318957 DOI: 10.1073/pnas.96.10.5758 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation